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Art. -Nr.: HY-B1118S3

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Secnidazole-d₃

(Synonyms: RP-14539-d₃; PM-185184-d₃)

Secnidazole-d₃ (RP-14539-d₃; PM-185184-d₃) is the deuterium labeled Secnidazole (HY-B1118). Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₇H₈D₃N₃O₃
Molecular Weight:188.20

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (248 KB)

Secnidazole-d₃ Chemical Structure

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Biologische Aktivität
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Biologische Aktivität

Beschreibung

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In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anwendung

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 3366-95-8
Molecular Weight 188.20
Formel C₇H₈D₃N₃O₃
SMILES

O=[N+]([O-])C(N1CC(O)C)=CN=C1C([2H])([2H])[2H]
Synonyms

RP-14539-d₃; PM-185184-d₃
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.