XAP044
Based on 1 Customer Validation
XAP044 is a potent and selective antagonist of mGlu7. The metabotropic glutamate receptor subtype 7 (mGlu7) is an important presynaptic regulator of neurotransmission in the mammalian CNS. XAP044 demonstrates good brain exposure and wide spectrum anti-stress and antidepressant- and anxiolytic-like efficacy in rodent behavioral paradigms.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.99%
- CAS. Nr.: 196928-50-4
- Formel: C15H9IO4
- Molecular Weight:380.13
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Speicherung:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Chemical Information
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CAS. Nr. 196928-50-4
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Appearance Solid
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Molecular Weight 380.13
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Formel C15H9IO4
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Color White to off-white
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SMILES
O=C1C2=CC=C(O)C=C2OC=C1OC3=CC=C(I)C=C3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Lösungsmittel & Löslichkeit
DMSO : ≥ 50 mg/mL (131.53 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6307 mL | 13.1534 mL | 26.3068 mL | 65.7670 mL |
| 5 mM | 0.5261 mL | 2.6307 mL | 5.2614 mL | 13.1534 mL | |
| 10 mM | 0.2631 mL | 1.3153 mL | 2.6307 mL | 6.5767 mL | |
| 15 mM | 0.1754 mL | 0.8769 mL | 1.7538 mL | 4.3845 mL | |
| 20 mM | 0.1315 mL | 0.6577 mL | 1.3153 mL | 3.2883 mL | |
| 25 mM | 0.1052 mL | 0.5261 mL | 1.0523 mL | 2.6307 mL | |
| 30 mM | 0.0877 mL | 0.4384 mL | 0.8769 mL | 2.1922 mL | |
| 40 mM | 0.0658 mL | 0.3288 mL | 0.6577 mL | 1.6442 mL | |
| 50 mM | 0.0526 mL | 0.2631 mL | 0.5261 mL | 1.3153 mL | |
| 60 mM | 0.0438 mL | 0.2192 mL | 0.4384 mL | 1.0961 mL | |
| 80 mM | 0.0329 mL | 0.1644 mL | 0.3288 mL | 0.8221 mL | |
| 100 mM | 0.0263 mL | 0.1315 mL | 0.2631 mL | 0.6577 mL |
XAP044 Related Classifications
HY-110146 Related Classifications
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