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Cat. No.: HY-161162

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aTAG 2139

(Synonyms: CFT-2139)

aTAG 2139 (CFT-2139) is an aTAG-based MTH1 fusion protein degrader with a DC₅₀ value of 1.1 nM. aTAG 2139 has a Ki value of 2.1 nM for MTH1.

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CAS No.: 2387510-81-6
Formule: C₄₂H₃₈N₈O₈
Masse moléculaire:782.80

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

aTAG 2139 Chemical Structure

CAS No.: 2387510-81-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

aTAG 2139 (CFT-2139) is an aTAG-based MTH1 fusion protein degrader with a DC₅₀ value of 1.1 nM. aTAG 2139 has a Ki value of 2.1 nM for MTH1^[1].

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Chemical Information

CAS No. 2387510-81-6
Masse moléculaire 782.80
Formule C₄₂H₃₈N₈O₈
SMILES

O=C(C1=CC=C(C2=CC=C3N=CC(C(NC)=O)=C(C3=C2)NC4=CC=CC=C4)C=N1)NCCCCNC(COC5=CC=CC(C(N6C7C(NC(CC7)=O)=O)=O)=C5C6=O)=O
Synonyms

CFT-2139
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Veits G K, et al. Development of an AchillesTAG degradation system and its application to control CAR-T activity[J]. Current Research in Chemical Biology, 2021, 1: 100010.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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aTAG 2139

Voir tous les produits spécifiques à Isoform DNA/RNA Synthesis

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

aTAG 2139 Related Classifications

HY-161162 Related Classifications