DM-PIT-1
Based on 1 Customer Validation
DM-PIT-1 is a PIP3/PH (phosphatidylinositol-3,4,5-triphosphate/Pleckstrin) interaction inhibitor. DM-PIT-1 decreases he expression of P-Akt, P-GSK-3-β, P-p70S6K, P-S6, P-4E-BP1. DM-PIT-1 induces apoptosis and shows anticancer activity. DM-PIT-1 has the potential for the research of ovarian cancer.
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- Pureté: 99.9%
- CAS No.: 701947-53-7
- Formule: C16H15N3O4S
- Masse moléculaire:345.37
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Stockage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
DM-PIT-1 (25, 50, 100 µM; 12 h) decreases he expression of P-Akt, P-GSK-3-β, P-p70S6K, P-S6, P-4E-BP1 in U87MG cells[2].
DM-PIT-1 (0-200 µM) inhibits cell viability for U87MG cells with an IC50 value of 33.9 µM[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 701947-53-7
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Appearance Solid
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Masse moléculaire 345.37
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Formule C16H15N3O4S
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Color Off-white to light yellow
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SMILES
O=C(C1=CC(C)=CC(C)=C1)NC(NC2=C(C=CC([N+]([O-])=O)=C2)O)=S
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Synonyms
3,5-Dimethyl PIT-1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Pureté et documentation
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Fiche technique (266 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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