(E)-PHCCC
(E)-PHCCC is a positive allosteric modulator (PAM) for mGluR4, that enhances the activity of the receptor's endogenous ligand (glutamate), and exhibits activity in the calcium mobilization assay in CHO cells with an EC50 of 3.2 μM.
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- CAS No.: 177610-87-6
- Formule: C17H14N2O3
- Masse moléculaire:294.30
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | IC50 |
3 μM
Compound: 4b
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Compound was tested for inhibition of glutamate-evoked (10 uM) [Ca2+] mobilization in mGluR1-alpha expressed-CHO cells.
Compound was tested for inhibition of glutamate-evoked (10 uM) [Ca2+] mobilization in mGluR1-alpha expressed-CHO cells.
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10.1016/0960-894X(96)00104-7 |
Chemical Information
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CAS No. 177610-87-6
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Masse moléculaire 294.30
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Formule C17H14N2O3
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SMILES
O=C(C12C(/C(C3=CC=CC=C3O2)=N\O)([H])C1)NC4=CC=CC=C4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(E)-PHCCC Related Classifications
HY-111332 Related Classifications
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