GI-129471
GI-129471 is a MMP inhibitor. GI-129471 exhibits inhibitory activity against cancer cell invasion. GI-129471 can completely block the enhanced production of IgE and IgG1 by mouse B cells induced by rat mast cell protease-I (RMCP-I). GI-129471 can be used for the study of cancer and mast cell chymase-regulated immunological processes.
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- CAS No.: 130370-59-1
- Formule: C25H33N3O4S
- Masse moléculaire:471.61
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Chemical Information
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CAS No. 130370-59-1
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Masse moléculaire 471.61
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Formule C25H33N3O4S
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SMILES
ONC([C@@H](CSC1=CC=CC=C1)[C@@H](CC(C)C)C(N[C@H](C(NC)=O)CC2=CC=CC=C2)=O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Kempen I, et al. 3-Bromophenyl 6-acetoxymethyl-2-oxo-2H-1-benzopyran-3-carboxylate inhibits cancer cell invasion in vitro and tumour growth in vivo. Br J Cancer. 2003 Apr 7;88(7):1111-8. [Content Brief]
[2]. Yoshikawa T, et al. Rat mast cell protease-I enhances immunoglobulin E production by mouse B cells stimulated with interleukin-4. Immunology. 2001 Nov;104(3):333-40. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)