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Cat. No.: HY-N12908

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Roridin H

Name: Roridin H
Brand: MedChemExpress
SKU: HY-N12908
Availability: PreOrder

(Synonyms: Verrucarin H)

Roridin H (Verrucarin H) is a cytostatic antibiotic present in the Myrothecium verrucaria strain and the marine-derived Myrothecium sp. TUF 02F6. The IC₅₀ of Roridin H against mouse leukemia cells is 0.12 mM. Roridin H can be used in leukemia-related research.

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CAS No.: 29953-50-2
Formule: C₂₉H₃₆O₈
Masse moléculaire:512.59

Stockage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Roridin H Chemical Structure

CAS No.: 29953-50-2

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Description

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Cellular Effect

Cell Line	Type	Value	Description	References
L1210	IC50	0.12 μM	Cytotoxicity against murine leukemia L1210 cells by XTT method, incubated for 72 h. Cytotoxicity against murine leukemia L1210 cells by XTT method, incubated for 72 h.	17080680

In Vitro

Roridin H (compound 1) undergoes complete catalytic hydrogenation to form Octahydrororidin H^[1].
Roridin H undergoes base-catalyzed hydrolysis, which cleaves the macrocyclic diester to produce Verrucarol and Myrothecinic acid^[1].
Roridin H (72 h) potently inhibits the proliferation of mouse leukemia L1210 cells, with an IC₅₀ of 0.12 μM^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 29953-50-2
Appearance Solid
Masse moléculaire 512.59
Formule C₂₉H₃₆O₈
Color White to off-white
SMILES

CC1=C[C@]2([H])[C@]([C@]3(C)[C@@]4(OC4)[C@](C[C@H]3OC(/C=C\C=C\C(O5)C(C)OC5C/C(C)=C\6)=O)([H])O2)(COC6=O)CC1
Synonyms

Verrucarin H
Structure Classification
- Antibiotics
- Macrolide Antibiotics
Initial Source
- Microorganisms
Myrothecium verrucaria
Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (290 KB)
SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Traxler P. Die Struktur des Antibioticums Roridin H. Verrucarine und Roridine, 20. Mitt. Helvetica Chimica Acta, 1970, 53(7):1846‑1869.

[2]. Xu J, et al. Four new macrocyclic trichothecenes from two strains of marine-derived fungi of the genus Myrothecium. The Journal of antibiotics. 2006 Aug;59(8):451-5.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Roridin H

Satratoxin G

Satratoxin H

Djalonensone

O-Methylsterigmatocystin

Territrem B

Stachybotrylactam

Fumitremorgin B

Fumonisin B4

Demethoxyviridiol

Territrem A

5-Acetamide-Butenolide

Janthitrem A

Voir tous les produits spécifiques à Isoform Antibiotic

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

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