TC113
TC113 is a c(RGDyK)-Based conjugate of Gemcitabine (GEM). TC113 could be internalized by A549 cells through integrin αvβ3. TC113 shows potent antiproliferative properties against WM266.4 and A549 cells.
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- Formule: C37H50F2N12O13
- Masse moléculaire:908.86
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
678.5 nM
Compound: TC113
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Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
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[PMID: 34967607] |
| WM 266-4 | IC50 |
57.6 μM
Compound: TC113
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Inhibition of cell growth in human WM266-4 cells measured after 24 hrs
Inhibition of cell growth in human WM266-4 cells measured after 24 hrs
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[PMID: 34967607] |
Chemical Information
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Masse moléculaire 908.86
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Formule C37H50F2N12O13
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SMILES
FC1(F)[C@H](O)[C@@H](COC(NCCCC[C@@H](C(N[C@@H](CCCNC(N)=N)C(NC2)=O)=O)NC([C@H](NC([C@@H](NC2=O)CC(O)=O)=O)CC3=CC=C(O)C=C3)=O)=O)O[C@H]1N4C=CC(N)=NC4=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TC113 Related Classifications
HY-145314 Related Classifications
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