Cyclin K degrader 2
Cyclin K degrader 2 is a molecular glucose degrading agent that targets the cyclin K protein. Cyclin K degrader 2 has inhibitory activity against CDK1 and CDK9. Cyclin K degrader 2 causes a decrease in RNA polymerase II Ser2 phosphorylation levels, downregulation of DNA damage response gene expression, accumulation of DNA damage, G1 phase arrest of the cell cycle, and apoptosis. Cyclin K degrader 2 can be used for cancer research.
For research use only. We do not sell to patients.
- Formula: C19H20N4OS2
- Molecular Weight:384.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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CDK1 |
CDK9 |
Chemical Information
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Molecular Weight 384.52
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Formula C19H20N4OS2
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SMILES
CN(C1=CC=C(C=C1)CC(NC2=NC=C(S2)SCC3=CC=CN=C3)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)