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Hesperidin

(Synonyms: Hesperetin 7-rutinoside)
36 Cited Publications
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Based on 36 publication(s) in Google Scholar

Hesperidin (Hesperetin 7-rutinoside), a flavanone glycoside, is isolated from citrus fruits. Hesperidin has numerous biological properties, such as decreasing inflammatory mediators and exerting significant antioxidant effects. Hesperidin also exhibits antitumor and antiallergic activities.

For research use only. We do not sell to patients.

  • Purity: 99.14%
  • CAS No.: 520-26-3
  • Formula: C28H34O15
  • Molecular Weight:610.56
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 2 years , -20°C, 1 year
  • Hesperidin Chemical Structure
    Hesperidin Chemical Structure
  • Experimental Validation Results for Hesperidin
  • Experimental Validation Results for Hesperidin
  • Experimental Validation Results for Hesperidin
  • Experimental Validation Results for Hesperidin
  • Experimental Validation Results for Hesperidin
  • Experimental Validation Results for Hesperidin
CAS No.: 520-26-3
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  • Hesperidin Chemical Structure
    Hesperidin Chemical Structure
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    Hesperidin purchased from MedChemExpress. Usage Cited in: Metabolism. 2025 Aug:169:156271. [Abstract]

    Customer Validation
     Eight–week–old NTG and OE–WWP1 C57 BL/6 J mice were intragastrically administered with the novel WWP1 inhibitor hesperidin (150 mg/kg body weight/day) and further fed an ND or HFHC for another 16 weeks. Average daily food intake (n = 6/group). Fecal TAG levels (n = 6/group). Liver organ index (n = 6/group). Energy expenditure (n = 6/group). Fasting blood glucose levels, fasting insulin levels, and HOMA–IR scores (n = 6/group).

  • 1/16

    Hesperidin purchased from MedChemExpress. Usage Cited in: Metabolism. 2025 Aug:169:156271. [Abstract]

    Customer Validation
     Eight–week–old NTG and OE–WWP1 C57 BL/6 J mice were intragastrically administered with the novel WWP1 inhibitor hesperidin (150 mg/kg body weight/day) and further fed an ND or HFHC for another 16 weeks. Western blot analysis of AKT phosphorylation in mouse livers (n = 2/group).

  • 1/16

    Hesperidin purchased from MedChemExpress. Usage Cited in: Metabolism. 2025 Aug:169:156271. [Abstract]

    Customer Validation
     Eight–week–old NTG and OE–WWP1 C57 BL/6 J mice were intragastrically administered with the novel WWP1 inhibitor hesperidin (150 mg/kg body weight/day) and further fed an ND or HFHC for another 16 weeks. H & E staining of mouse liver sections (n = 6/group). Oil Red O depicting hepatic lipid droplets; scale bar, 50 μm.

  • 1/16

    Hesperidin purchased from MedChemExpress. Usage Cited in: Metabolism. 2025 Aug:169:156271. [Abstract]

    Customer Validation
     Eight–week–old NTG and OE–WWP1 C57 BL/6 J mice were intragastrically administered with the novel WWP1 inhibitor hesperidin (150 mg/kg body weight/day) and further fed an ND or HFHC for another 16 weeks. RT–qPCR analysis of the mRNA levels of genes involved in hepatic inflammation (n = 6/group).

  • 1/16

    Hesperidin purchased from MedChemExpress. Usage Cited in: Metabolism. 2025 Aug:169:156271. [Abstract]

    Customer Validation
     Eight–week–old NTG and OE–WWP1 C57 BL/6 J mice were intragastrically administered with the novel WWP1 inhibitor hesperidin (150 mg/kg body weight/day) and further fed an ND or HFHC for another 16 weeks. Western blot detecting expressions of NF–κB pathways in livers (n = 2/group).

  • 1/16

    Hesperidin purchased from MedChemExpress. Usage Cited in: Cell Rep. 2017 Nov 21;21(8):2147-2159. [Abstract]

    Customer Validation
     U2OS cells expressing Myc-tagged PLK1 WT, K492R, or SUMO-1-K492R are treated with NSC 125973 for 16 hr. Half of the cells are then released in the presence of Hesperidin for 45 min to enrich cells at the later stage of M phase. Cell lysates are subject to IP, followed by western blot.

  • Hesperidin