Fasudil hydrochloride solution

(Synonyms: HA-1077 hydrochloride solution; AT-877 hydrochloride solution)

Fasudil hydrochloride solution is mainly composed of Fasudil hydrochloride (HY-10341). Fasudil (HA-1077; AT877) hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil hydrochloride is also a potent Ca2+ channel antagonist and vasodilator,and can improve and prevent cerebral vasospasm after subarachnoid hemorrhage surgery and the resulting cerebral ischemic symptoms.

For research use only. We do not sell to patients.

  • CAS No.: 105628-07-7
  • Formula: C14H18ClN3O2S
  • Molecular Weight:327.83
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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