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Cat. No.: HY-123605

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CAY10406

CAY10406 is an inhibitor for caspase 3/7. CAY10406 inhibits the expression of 28-kDa IL-1β fragment, without significant cytotoxicity (10 μM).

For research use only. We do not sell to patients.

CAS No.: 2108603-03-6
Formula: C₂₇H₂₃F₃N₂O₅S
Molecular Weight:544.54

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

CAY10406 Chemical Structure

CAS No.: 2108603-03-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

CAY10406 is an inhibitor for caspase 3/7. CAY10406 inhibits the expression of 28-kDa IL-1β fragment, without significant cytotoxicity (10 μM)^[1].

All Caspase Isoforms :

Chemical Information

CAS No. 2108603-03-6
Molecular Weight 544.54
Formula C₂₇H₂₃F₃N₂O₅S
SMILES

O=S(C1=CC=C(C(C(C2=O)=O)=C1)N2CC3=CC=CC=C3)(N4[C@@H](CCC4)COC5=CC=C(C=C5)C(F)(F)F)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Pathak S, et al., Autoimmune inner ear disease patient-associated 28-kDa proinflammatory IL-1β fragment results from caspase-7-mediated cleavage in vitro. JCI Insight. 2020 Feb 13;5(3):e130845. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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CAY10406

Z-Phe-Tyr(tBu)-diazomethylketone

Fluostatin B

Z-AEVD-FMK

Ac-LEHD-AMC

Fluostatin A sodium

Z-IETD-AFC

Boc-Glu-OBzl

Ac-LETD-AFC

Ac-DNLD-AMC

All Caspase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

CAY10406

Z-Phe-Tyr(tBu)-diazomethylketone

Fluostatin B

Z-AEVD-FMK

Ac-LEHD-AMC

Fluostatin A sodium

Z-IETD-AFC

Boc-Glu-OBzl

Ac-LETD-AFC

Ac-DNLD-AMC

All Caspase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

CAY10406 Related Classifications

HY-123605 Related Classifications