1. Epigenetics
  2. Histone Methyltransferase
  3. FTX-6058 hydrochloride

FTX-6058 hydrochloride 

Cat. No.: HY-139400A
Handling Instructions

FTX-6058 hydrochloride is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED). FTX-6058 hydrochloride can induce HbF protein expression in cell and murine models. FTX-6058 hydrochloride can be used for the research of select hemoglobinopathies, including sickle cell disease and β-thalassemia.

For research use only. We do not sell to patients.

FTX-6058 hydrochloride Chemical Structure

FTX-6058 hydrochloride Chemical Structure

CAS No. : 2490676-19-0

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Description

FTX-6058 hydrochloride is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED). FTX-6058 hydrochloride can induce HbF protein expression in cell and murine models. FTX-6058 hydrochloride can be used for the research of select hemoglobinopathies, including sickle cell disease and β-thalassemia[1][2].

In Vitro

FTX-6058 hydrochloride inhibits PRC2 via binding to EED, which induces robust HbF protein expression in both cell and murine models[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

439.87

Formula

C₂₂H₁₉ClFN₅O₂

CAS No.
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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
FTX-6058 hydrochloride
Cat. No.:
HY-139400A
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