Hydrodolasetron
Based on 1 Customer Validation
Hydrodolasetron is a metabolite of Dolasetron (HY-B0750). Hydrodolasetron is more potent than Dolasetron in inhibiting nAChR. Hydrodolasetron is a 5-HT(3A)R blocker with an IC50 of 0.29 nM. Hydrodolasetron has antiemetic activity.
For research use only. We do not sell to patients.
- Purity : 98.96%
- CAS No.: 127951-99-9
- Formula: C19H22N2O3
- Molecular Weight:326.39
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All 5-HT Receptor Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 127951-99-9
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Appearance Solid
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Molecular Weight 326.39
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Formula C19H22N2O3
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Color White to off-white
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SMILES
O=C(C1=CNC2=C1C=CC=C2)OC3CC4N5CC(O)C(C4)CC5C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)