Ceftibuten
Based on 2 publication(s) in Google Scholar
Ceftibuten (Sch39720), an antibiotic, is an orally active cephalosporin, possesses potent activity in vitro against a wide range of gram-negative and certain gram-positive pathogens.
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- No. CAS: 97519-39-6
- Fòrmula: C15H14N4O6S2
- Peso molecular:410.42
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Publications Citing Use of MedChemExpress (MCE) Ceftibuten
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Actividad biológica
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β-lactam |
Ceftibuten (Sch39720) is highly active against Haemophilus influenza, Escherichia coli, Klebsiella sp., and Proteus sp. and moderately active against Serratia sp. and Streptococcus pyogenes. Ceftibuten is relatively inactive against enterococci and staphylococci and is only weakly active against Pseudomonas aeruginosa and obligate anaerobes. It is also stable in the presence of most β-lactamase-producing organisms except βBacteroides fragilis. Ceftibuten is very active against strains of the family Enterobacteriaceae (mean MIC for 90% of strains=0.25 μg/ml) but less active against Campylobacterjejuni (mean MIC for 90% of strains=16.0 μg/ml)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 97519-39-6
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Peso molecular 410.42
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Fòrmula C15H14N4O6S2
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SMILES
O=C(C(N12)=CCS[C@]2([H])[C@H](NC(/C(C3=CSC(N)=N3)=C\CC(O)=O)=O)C1=O)O
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Synonyms
Sch 39720
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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SLAS Discov
2020 Sep;25(8):895-905. PMID: 32567455 -
Pureza y Documentación
Referencias
[1]. Kearns GL, et al. Single-dose pharmacokinetics of ceftibuten (SCH 39720) in infants and children. Antimicrob Agents Chemother. 1991;35(10):2078-2084. [Content Brief]
[2]. Shawar R, et al. Comparative in vitro activity of ceftibuten (Sch 39720) against bacterial enteropathogens. Antimicrob Agents Chemother. 1989;33(5):781-784. [Content Brief]
[3]. Tamai I, et al. Functional expression of intestinal dipeptide/beta-lactam antibiotic transporter in Xenopus laevis oocytes. Biochem Pharmacol. 1994;48(5):881-888. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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