DS22
DS22 is a CDK12-cyclin K molecular glue degrader. DS22 promotes the formation of the DDB1-CDK12-cyclin K ternary complex, with an EC50 of 19 nM. DS22 can be used in research related to CDK12-mediated diseases, such as cancer.
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- No. CAS: 3068547-01-0
- Fòrmula: C21H22Cl2N10O
- Peso molecular:501.37
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
IC50 & Target
[1]|
CDK12/Cyclin K 1316 nM (IC50) |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 3068547-01-0
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Peso molecular 501.37
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Fòrmula C21H22Cl2N10O
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SMILES
CC[C@@H](NC1=NC(NCC2=NC3=CC(Cl)=C(Cl)C=C3N2)=C4C(N(C5=CN(C)N=C5)C=N4)=N1)CO
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DS22 Related Classifications
HY-190189 Related Classifications
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