EA-89
EA-89 is a potent and selective BRD9 inhibitor with antitumor activity. EA-89 is a Ligand for Target Protein for PROTAC. EA-89 can be used to synthesize PROTAC QA-68 (HY-150797).
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C31H38N4O4S2
- Peso molecular:594.79
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
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BRD9 |
EA-89 (0-3.2 μM; 1-7 days) inhibits cell proliferation and expression of BRD9, c-MYC and c-MYB in human leukemia cell lines[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:SKM-1 cells
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Concentration:0, 10, 100, 1000 nM
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Incubation Time:24 h
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Result:Reduced the levels of c-MYC and c-MYB.
Chemical Information
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Peso molecular 594.79
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Fòrmula C31H38N4O4S2
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SMILES
CCCN1C=C(C2=CC=C(N(CC3CCNCC3)C=C4C)C4=C2)C5=C(C=C(S5)C(NC6CCS(CC6)(=O)=O)=O)C1=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EA-89 Related Classifications
HY-170314 Related Classifications
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