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Referencia número: HY-N3943

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Glabrene

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

Glabrene, an isoflavene derived from licorice root, shows estrogen-like activity. Glabrene is a tyrosinase inhibitor with an IC₅₀ of 3.5 μM.

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No. CAS: 60008-03-9
Fòrmula: C₂₀H₁₈O₄
Peso molecular:322.35

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Glabrene Chemical Structure

No. CAS: 60008-03-9

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Actividad biológica
- Descripciòn
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Publications (1)
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Actividad biológica

Descripciòn

Glabrene, an isoflavene derived from licorice root, shows estrogen-like activity. Glabrene is a tyrosinase inhibitor with an IC₅₀ of 3.5 μM^[1]^[2].

IC₅₀ & Target

IC50: 3.5 μM (Tyrosinase)^[2]

Cellular Effect

Cell Line	Type	Value	Description	References
RAW264.7	IC₅₀	9.5 μM Compound: 15	Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay	[PMID: 28140583]

Chemical Information

No. CAS 60008-03-9
Peso molecular 322.35
Fòrmula C₂₀H₁₈O₄
SMILES

OC1=C2C=CC(C)(C)OC2=C(C3=CC4=CC=C(O)C=C4OC3)C=C1
Structure Classification
- Phenols
- Polyphenols
- Stilbenes
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Pureza: 99.98%

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ee.: 99.98%

Ficha de datos (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Somjen D, et al. Estrogenic activity of glabridin and glabrene from licorice roots on human osteoblasts and prepubertal rat skeletal tissues. J Steroid Biochem Mol Biol. 2004 Aug;91(4-5):241-6. [Content Brief]

[2]. Nerya O, et al. Glabrene and isoliquiritigenin as tyrosinase inhibitors from licorice roots. J Agric Food Chem. 2003 Feb 26;51(5):1201-7 [Content Brief]

Calculators

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1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Glabrene

1 Cited Publications

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Actividad biológica
- Descripciòn
- IC₅₀ & Target
Chemical Information
Publications (1)
Pureza y Documentación
Referencias

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Glabrene

Publications Citing Use of MedChemExpress (MCE) Glabrene

Actividad biológica

Chemical Information

Publications (1)

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Referencias

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Glabrene Related Classifications

HY-N3943 Related Classifications