VUF11207 TFA
Based on 3 publication(s) in Google Scholar
VUF11207 (Compound 29) TFA is a CXCR7 agonist (pKi of 8.1) that induces recruitment of β-arrestin2 (pEC50 of 8.8) and subsequent internalization (pEC50 of 7.9) of CXCR7.
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- No. CAS: 1492153-74-8
- Fòrmula: C29H36F4N2O6
- Peso molecular:584.60
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Actividad biológica
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CXCR7 8.1 (pKi) |
Chemical Information
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No. CAS 1492153-74-8
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Peso molecular 584.60
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Fòrmula C29H36F4N2O6
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SMILES
O=C(N(C/C(C)=C/C1=CC=CC=C1F)CCC2N(C)CCC2)C3=CC(OC)=C(OC)C(OC)=C3.FC(C(O)=O)(F)F
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (3)
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Journal Impact Factor
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Most Recent
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Immunity
Spatiotemporal dynamics of CXCL10 encode contextual immune information revealed by the genetically encoded fluorescent sensor. [Abstract]2025 Sep 9;58(9):2320-2335.e9. PMID: 40818452 -
Cell Death Dis
CXCR7 activation evokes the anti-PD-L1 antibody against glioblastoma by remodeling CXCL12-mediated immunity. [Abstract]2024 Jun 19;15(6):434. PMID: 38898023 -
Cell Mol Life Sci
Crosstalk between purinergic receptor P2Y11 and chemokine receptor CXCR7 is regulated by CXCR4 in human macrophages. [Abstract]2024 Mar 13;81(1):132. PMID: 38472446
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Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
VUF11207 TFA Related Classifications
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