CCL4 - C-C motif chemokine ligand 4 Gene

Also Known as ACT2; G-26; HC21; LAG1; LAG-1; MIP1B; SCYA2; SCYA4; MIP1B1; AT744.1; MIP-1-beta

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 6351

About CCL4

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:36,103,827-36,105,614 (from NCBI)

This gene has 3 transcripts (splice variants), 1 gene allele, 194 orthologues and 25 paralogues. Broad expression in bone marrow (RPKM 61.4), liver (RPKM 36.1) and 18 other tissues.

Summary

The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. [provided by RefSeq, Dec 2012]

CCL4 Products (1)

mRNA	Protein	Name
NM_002984.4	NP_002975.1	C-C motif chemokine 4 precursor

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	References	Source
enables CCR1 chemokine receptor binding	IPI IPI: Inferred from physical interaction	7545673	GOA
enables CCR5 chemokine receptor binding	IPI IPI: Inferred from physical interaction	10383387	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	20959807	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	23597562	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in negative regulation by host of viral transcription	IDA IDA: Inferred from direct assay	10841574	GOA
involved in positive regulation of calcium ion transport	IDA IDA: Inferred from direct assay	8699119	GOA
involved in positive regulation of calcium-mediated signaling	IMP IMP: Inferred from mutant phenotype	10679098	GOA
involved in positive regulation of natural killer cell chemotaxis	IDA IDA: Inferred from direct assay	7545673	GOA
involved in response to toxic substance	IDA IDA: Inferred from direct assay	10841574	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CCL4 Protein Structure

IL8

0
92 a.a.

Protein Preferred Names	Protein Names
C-C motif chemokine 4	G-26 T-lymphocyte-secreted protein

CCL4 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	CCL4	P13236	SLC30A8	Homo sapiens	Q8IWU4	Validated Y2H	32296183
Intra	CCL4	P13236	SLC30A8	Homo sapiens	Q8IWU4	Y2H Prey Pooling	32296183
Intra	CCL4	P13236	SLC30A8	Homo sapiens	Q8IWU4	Y2H Array	32296183
Intra	CCL4	P13236	MARCHF2	Homo sapiens	Q9P0N8	Validated Y2H	32296183
Intra	CCL4	P13236	ARL13B	Homo sapiens	Q3SXY8	Y2H Prey Pooling	32296183
Intra	CCL4	P13236	ARL13B	Homo sapiens	Q3SXY8	Validated Y2H	32296183
Intra	CCL4	P13236	ARL13B	Homo sapiens	Q3SXY8	Y2H Array	32296183
Intra	CCL4	P13236	TMEM179B	Homo sapiens	Q7Z7N9	Y2H Array	32296183
Intra	CCL4	P13236	TMEM179B	Homo sapiens	Q7Z7N9	Y2H Prey Pooling	32296183
Intra	CCL4	P13236	TMEM179B	Homo sapiens	Q7Z7N9	Validated Y2H	32296183
Intra	CCL4	P13236	GPRC5D	Homo sapiens	Q9NZD1	Y2H Array	32296183
Intra	CCL4	P13236	GPRC5D	Homo sapiens	Q9NZD1	Y2H Prey Pooling	32296183
Intra	CCL4	P13236	GPRC5D	Homo sapiens	Q9NZD1	Validated Y2H	32296183
Intra	CCL4	P13236	GPR152	Homo sapiens	Q8TDT2	Y2H Prey Pooling	32296183
Intra	CCL4	P13236	GPR152	Homo sapiens	Q8TDT2	Validated Y2H	32296183
Intra	CCL4	P13236	GPR152	Homo sapiens	Q8TDT2	Y2H Array	32296183
Intra	CCL4	P13236	UNC93A	Homo sapiens	Q86WB7-2	Validated Y2H	32296183
Intra	CCL4	P13236	UNC93A	Homo sapiens	Q86WB7-2	Y2H Array	32296183
Intra	CCL4	P13236	UNC93A	Homo sapiens	Q86WB7-2	Y2H Prey Pooling	32296183
Intra	CCL4	P13236	GJA8	Homo sapiens	P48165	Y2H Prey Pooling	32296183
Intra	CCL4	P13236	GJA8	Homo sapiens	P48165	Validated Y2H	32296183
Intra	CCL4	P13236	GJA8	Homo sapiens	P48165	Y2H Array	32296183
Intra	CCL4	P13236	SLC18A1	Homo sapiens	P54219-3	Validated Y2H	32296183
Intra	CCL4	P13236	SLC18A1	Homo sapiens	P54219-3	Y2H Prey Pooling	32296183
Intra	CCL4	P13236	SLC18A1	Homo sapiens	P54219-3	Y2H Array	32296183
Intra	CCL4	P13236	TAS2R5	Homo sapiens	Q9NYW4	Y2H Prey Pooling	32296183
Intra	CCL4	P13236	TAS2R5	Homo sapiens	Q9NYW4	Validated Y2H	32296183
Intra	CCL4	P13236	TAS2R5	Homo sapiens	Q9NYW4	Y2H Array	32296183
Intra	CCL4	P13236	SLC10A6	Homo sapiens	Q3KNW5	Y2H Prey Pooling	32296183
Intra	CCL4	P13236	SLC10A6	Homo sapiens	Q3KNW5	Validated Y2H	32296183
Intra	CCL4	P13236	TMEM86B	Homo sapiens	Q8N661	Y2H Prey Pooling	32296183
Intra	CCL4	P13236	TMEM86B	Homo sapiens	Q8N661	Validated Y2H	32296183
Intra	CCL4	P13236	TMEM86B	Homo sapiens	Q8N661	Y2H Array	32296183
Intra	CCL4	P13236	CNR2	Homo sapiens	P34972	Validated Y2H	32296183
Intra	CCL4	P13236	CNR2	Homo sapiens	P34972	Y2H Array	32296183
Intra	CCL4	P13236	CNR2	Homo sapiens	P34972	Y2H Prey Pooling	32296183
Intra	CCL4	P13236	SLC30A2	Homo sapiens	Q9BRI3	Y2H Array	31515488
Intra	CCL4	P13236	ccsb orf id: 2260	Homo sapiens	EBI-22326698	Y2H Prey Pooling	32296183
Intra	CCL4	P13236	CCL4	Homo sapiens	P13236	X-Ray Diffraction	20959807
Intra	CCL4	P13236	CCL4	Homo sapiens	P13236	GMS	20959807
Intra	CCL4	P13236	SLC30A2	Homo sapiens	Q9BRI3	Validated Y2H	32296183
Intra	CCL4	P13236	CCL4	Homo sapiens	P13236	SAXS	20959807
Intra	CCL4	P13236	ccsb orf id: 2260	Homo sapiens	EBI-22326698	Y2H Array	32296183
Intra	CCL4	P13236	SLC30A2	Homo sapiens	Q9BRI3	Y2H Array	32296183
Intra	CCL4	P13236	SLC30A2	Homo sapiens	Q9BRI3	Y2H Prey Pooling	32296183
Intra	CCL4	P13236	SLC7A1	Homo sapiens	P30825	Y2H Array	32296183
Intra	CCL4	P13236	SLC7A1	Homo sapiens	P30825	Y2H Prey Pooling	32296183
Intra	CCL4	P13236	SLC7A1	Homo sapiens	P30825	Validated Y2H	32296183
Intra	CCL4	P13236	MRM1	Homo sapiens	Q6IN84	Validated Y2H	32296183
Intra	CCL4	P13236	MRM1	Homo sapiens	Q6IN84	Y2H Prey Pooling	32296183
Intra	CCL4	P13236	MRM1	Homo sapiens	Q6IN84	Y2H Array	32296183
Intra	CCL4	P13236	TIMMDC1	Homo sapiens	Q9NPL8	Y2H Array	32296183
Intra	CCL4	P13236	TIMMDC1	Homo sapiens	Q9NPL8	Y2H Prey Pooling	32296183
Intra	CCL4	P13236	TIMMDC1	Homo sapiens	Q9NPL8	Validated Y2H	32296183
Intra	CCL4	P13236	TMEM14B	Homo sapiens	Q9NUH8	Y2H Array	32296183
Intra	CCL4	P13236	TMEM14B	Homo sapiens	Q9NUH8	Validated Y2H	32296183
Intra	CCL4	P13236	TMEM14B	Homo sapiens	Q9NUH8	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant CCL4 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7257	CCL4 Protein, Human	P13236 (A24-N92)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P74342	CCL4 Protein, Human (P.pastoris, His)	P13236/NP_002975.1 (A24-N92)	≥ 90%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases	Alias
Adiposis Dolorosa	Dercum Disease Dercum'S Disease Lipomatosis Dolorosa Adiposalgia Adipose Tissue Rheumatism Anders Syndrome Dercum-Vitaut Syndrome Morbus Dercum
Human Immunodeficiency Virus Infectious Disease	Hiv Infections
Bacterial Meningitis	Meningitis, Bacterial Meningitis Bacterial Bm - [Bacterial Meningitis] Leptomeningitis Bacterial Pachymeningitis Bacterial Arachnoiditis Bacterial
Meconium Aspiration Syndrome	Neonatal Aspiration Of Meconium Meconium Aspiration Mas Meconium Aspiration Syndrome Of Newborn Meconium Inhalation Mas - [Meconium Aspiration Syndrome] Meconium Aspiration Nos Meconium Aspiration Syndrome Nos Meconium Pneumonitis Meconium Stained Liqueur Aspiration
Meningitis	Streptococcal Meningitis Acute Streptococcal Meningitis Staphylococcal Meningitis Adenoviral Meningitis Influenza Meningitis Influenzal Meningitis Meningitis Due To H. Influenzae Cryptococcal Meningitis Fungal Meningitis Due To Cryptococcus Neoformans Cryptococcosis Meningitis Cryptococcus Meningitis Cryptococcal Meningoencephalitis Meningitis Due To Cryptococcus Mumps Virus Meningitis Mumps Meningitis
Neuritis	Peripheral Neuritis
Whiplash
Anal Margin Squamous Cell Carcinoma	Perianal Skin Squamous Cell Carcinoma Squamous Cell Carcinoma Of Anal Margin
Retinal Vasculitis
Erdheim-Chester Disease	Ecd Erdheim Chester Disease Lipoid Granulomatosis Lipid Granulomatosis Polyostotic Sclerosing Histiocytosis
Radiculopathy	Pinched Nerve Nerve Root Disorder Radiculopathy, Site Unspecified Radicular Neuropathy Radicular Syndrome Radicular Pain Radiculitis Radiculitis Nos Spinal Root Pain Nerve Root Neuritis Radiculopathy In Spondylosis
Tropical Spastic Paraparesis	Tropical Spastic Paraplegia Ham/Tsp Htlv-Associated Myelopathy Tropical Spastic Paralysis Htlv-1 Associated Myelopathy/Tropical Spastic Paraparesis Human T-Cell Leukemia Virus Type 1 Associated Myelopathy/Tropical Spastic Paraparesis Htlv-1-Associated Myelopathy/Tropical Spastic Paraparesis Human T-Lymphotropic Virus Type I-Associated Myelopathy/Tropical Spastic Paraparesis Human T-Lymphotropic Virus Type-1-Associated Myelopathy/Tropical Spastic Paraparesis Tsp Paraparesis Tropical Spastic Paraparesis, Tropical Spastic
Castleman Disease	Angiofollicular Ganglionic Hyperplasia Angiofollicular Lymph Hyperplasia Giant Lymph Node Hyperplasia Castleman'S Disease Angiofollicular Lymph Node Hyperplasia Lymphoid Hamartoma Benign Giant Lymphoma Angiolymphoid Hyperplasia
Vaccinia
Polyradiculoneuropathy
Plasmodium Falciparum Malaria	Falciparum Malaria Malaria, Falciparum Malaria Fever, Subtertian Malignant Tertian Fever Malaria Falciparum Cerebral Malaria Nos Cerebral Malaria
Bone Disease	Bone Diseases Skeletal Disease Skeletal Disorder Disorder Of Skeletal System
Periapical Granuloma	Apical Granuloma
Pulmonary Tuberculosis	Tuberculosis, Pulmonary PTB Tuberculosis Pulmonary
Immune Deficiency Disease	Immunodeficiency Primary Immunodeficiency Primary Immunodeficiency Disease Immunologic Deficiency Syndromes Hypoimmunity Immune Deficiency Disorder Immunodeficiency Syndrome Immune Disorder Primary Immune Deficiency Disorder Immune System Diseases Human Immunodeficiency Virus Infection Hiv - [Human Immunodeficiency Virus Infection] Hiv Positive Nos Hiv Disease Acquired Immune Deficiency Syndrome-Related Complex Aids-Like Syndrome Aids-Related Complex Nos Arc - [Aids-Related Complex] Immunodeficiency Due To Human Immunodeficiency Virus Infection Unspecified Human Immunodeficiency Virus Disease Hiv Disease Nos Human Immunodeficiency Virus Positive Nos Hiv Nos Deficiency Of Complement Initial Pathway Deficiency Of Complement Terminal Pathway Cfdd - [Complement Factor D Deficiency] Immunodeficiency With Nk-Cell - [Natural-Killer Cell] Deficiency Nonfamilial Hypogammaglobulinaemia Common Variable Immune Deficiency Nonfamilial Agammaglobulinaemia Common Variable Agammaglobulinaemia Agammaglobulinaemia Nos Agammaglobulinaemia Antibody Deficiency Syndrome Hypogammaglobulinaemia Antibody Deficiency Syndrome Acquired Agammaglobulinaemia Nos Hypogammaglobulinaemia Nos Hyper Igm
Eosinophilic Pneumonia	Pneumonia, Eosinophilic Pulmonary Eosinophilia Asthmatic Pulmonary Eosinophilia Pneumonia Eosinophilic Simple Pulmonary Eosinophilia Eosinophilic Asthma
Dengue Disease	Dengue Fever Dengue Df Dengue Shock Syndrome Dengue Virus Infection Breakbone Fever Classic Dengue Classical Dengue Dengue Hemorrhagic Fever Hemorrhagic Dengue Philippine Hemorrhagic Fever Singapore Hemorrhagic Fever Thai Hemorrhagic Fever Severe Dengue Dengue Fever Without Warning Signs Dengue Haemorrhagic Fever Grade 1 Dengue Haemorrhagic Fever Without Warning Signs Bangkok Haemorrhagic Fever Singapore Haemorrhagic Fever Thailand Haemorrhagic Fever Southeast Asia Haemorrhagic Fever Dhf -[Dengue Haemorrhagic Fever] Dengue Fever With Warning Signs Dengue Haemorrhagic Fever With Warning Signs Dengue Haemorrhagic Fever Grade 2 Philippine Haemorrhagic Fever
Lipomatosis	Benign Symmetrical Lipomatosis
Uveitis
Late Congenital Syphilis	Juvenile Neurosyphilis Neurosyphilis, Juvenile
Viral Infectious Disease	Viral Disease Arbovirus Infections Virus Infection Virus Diseases Viral Infection Viral Infections Virus Infections
Anal Margin Carcinoma	Carcinoma Of Anal Margin Perianal Skin Carcinoma
Malaria	Malaria, Susceptibility To Malaria, Resistance To Malaria, Cerebral Cerebral Malaria Malaria, Severe, Susceptibility To Malaria, Severe, Resistance To Malaria, Cerebral, Susceptibility To Induced Malaria Malaria, Vivax, Protection Against Malaria, Severe Malaria, Cerebral, Reduced Risk Of Malaria, Protection Against Resistance To Malaria Due To G6pd Deficiency Malaria Due To G6pd Deficiency Malarial Encephalitis CM Malaria Cerebral Susceptibility To Malaria Acute Pernicious Fever Aestivo-Autumnal Fever Aestivo Autumnal Malaria Chagres Fever Continued Malaria Fever Estivo-Autumnal Fever Estivo-Autumnal Malaria Estivo-Autumnal Malarial Fever Falciparum Fever Malignant Tertian Fever Malignant Tertian Malaria Pernicious Intermittent Fever Pernicious Malaria Quotidian Malaria Subtertian Fever Subtertian Malaria Fever Subtertian Malignant Tertian Malaria Tropical Malaria Algid Malaria Bilious Haemoglobinuric Fever Black Water Fever Blackwater Fever Malarial Blackwater Fever Severe Malarial Falciparum West African Fever Malarial Haematinuria Haemoglobinuric Fever Haemoglobinuric Malaria Severe Plasmodium Falciparum Malaria Malarial Haemoglobinuria Malarial Haematuria Falciparum Malaria [Malignant Tertian] Malaria Tropica Malarial Shock Chagres Virus Disease Malignant Malaria Mtm - [Malignant Tertian Malaria] Tm -[Malignant Tertian Malaria] Panama Fever St - [Subtertian Malaria] Malarial Quotidian Benign Tertian Malaria Tertian Ague Vivax Fever Plasmodium Vivax Malaria Nos Btm - [Benign Tertian Malaria] Bt - [Benign Tertian Malaria] Vivax Malaria Benign Tertian Vivax Malaria Tertian Malaria Quartan Malaria Quartan Ague Quartan Fever Plasmodium Malariae Malaria Nos Quartan Malarial Malaria By Plasmodium Malariae Malariae Malaria Ovale Tertian Malaria Plasmodium Ovale Fever Malaria Fever By Plasmodium Ovale Ovale Malaria Malaria By Plasmodium Ovale Malarial Ovale Marsh Fever Remittent Congestive Fever Coastal Fever Remittent Gastric Fever Miasmatic Fever Congestive Remittent Fever Intermittent Fever Jungle Fever Paludism Cameroon Fever Ague Corsican Fever Intermittent Bilious Fever Disease Due To Plasmodiidae Malarial Fever Plasmodiosis Remittent Fever Roman Fever Malaria Fever Nos Malaria Nos Paludal Fever Clinically Diagnosed Malaria Clinically Diagnosed Malaria Without Parasitological Confirmation Congestive Fever Malarial Cachexia Marsh Cachexia Paludal Cachexia Recurrent Malaria Remittent Malaria
Bronchiolitis
Relapsing-Remitting Multiple Sclerosis	Relapsing-Remitting Ms Relapsing Remitting Multiple Sclerosis Multiple Sclerosis, Relapsing-Remitting Rrms Multiple Sclerosis Relapsing-Remitting
Encephalitis	Mumps Encephalitis Mumps Meningoencephalitis Herpes Simplex Neuroinvasion Herpetic Encephalitis Herpetic Encephalopathy Herpes Simplex Encephalitis, Myelitis Or Encephalomyelitis Encephalitis Due To Herpesviridae Encephalitis Due To Herpesvirus Herpes Encephalitis Herpesviral Encephalitis Herpes Simplex Encephalitis Hsv - [Herpes Simplex Virus] Encephalitis Herpes Virus Encephalitis Simian B Disease Simian B Disorder Encephalitis Nec Idiopathic Encephalitis
Human Immunodeficiency Virus Type 1	Aids Hiv/Aids Aids, Delayed/Rapid Progression To Hiv-1, Susceptibility To Hiv-1 Viremia, Susceptibility To Human Immunodeficiency Virus Type 1, Susceptibility To Hiv-1 Aids, Slow Progression To Rapid Progression To Aids From Hiv1 Infection Hiv1 Infection, Resistance To Hiv1 Infection Hiv-1 Viremia Aids, Resistance To Aids, Rapid Progression To Hiv/Aids, Susceptibility To Hiv-1, Resistance To Hiv1, Resistance To Hiv1 Hiv-1 Disease, Delayed Progression Of Hiv-1 Disease, Rapid Progression Of Hiv Infection, Resistance To Hiv Type 1, Susceptibility To Hiv Type 1 Hiv-1 Infection Human Immunodeficiency Virus I Infection Acquired Immunodeficiency Syndrome Hiv-Infection/Aids
Endocarditis
Interstitial Lung Disease 2	Idiopathic Pulmonary Fibrosis Ipf Fibrocystic Pulmonary Dysplasia Pulmonary Fibrosis, Idiopathic Pulmonary Fibrosis, Idiopathic, Susceptibility To Cryptogenic Fibrosing Alveolitis ILD2 Idiopathic Pulmonary Fibrosis, Familial Fibrosing Alveolitis, Cryptogenic Uip Fibrosing Alveolitis Interstitial Pneumonitis, Usual Familial Idiopathic Pulmonary Fibrosis Idiopathic Fibrosing Alveolitis, Chronic Form Usual Interstitial Pneumonia Fibrosing Alveolitis Cryptogenic Hamman-Rich Disease Idiopathic Pulmonary Fibrosis Familial Interstitial Pneumonitis Usual Fibrosis Idiopathic Pulmonary Fibrosis, Pulmonary, Idiopathic Hamman-Rich Syndrome Chronic Idiopathic Pulmonary Fibrosis Acute Interstitial Pneumonia Interstitial Pulmonary Fibrosis Ipf - [Idiopathic Pulmonary Fibrosis] Idiopathic Lung Fibrosis Fibrosing Lung Disease Pulmonary Fibrosis Nos Fibrosing Pneumonitis
Disease By Infectious Agent	Infectious Disease Infectious Diseases
Retinal Detachment	Retinal Detachments Rhegmatogenous Retinal Detachment Ruptured Retina With Detachment Retinal Hole With Detachment
Mast-Cell Leukemia	Mast Cell Leukemia Leukemia, Mast-Cell Leukemia Mast Cell Mast Cell Leukaemia Nos Mast Cell Leukaemia Without Mention Of Remission
Pancreatic Cancer	Pancreatic Carcinoma Carcinoma Of Pancreas Familial Pancreatic Carcinoma Pancreatic Neoplasm Pancreatic Carcinoma, Familial Malignant Neoplasm Of Pancreas Pancreatic Acinar Carcinoma Pancreatic Tumor Familial Pancreatic Cancer Neoplasm Of The Pancreas Cancer Of The Pancreas Pancreatic Carcinoma, Somatic Pancreatic Cancer, Somatic Ca Body Of Pancreas Ca Head Of Pancreas Ca Tail Of Pancreas Malignant Neoplasm Of Body Of Pancreas Malignant Neoplasm Of Head Of Pancreas Malignant Neoplasm Of Tail Of Pancreas Pancreas Neoplasm Exocrine Cancer Exocrine Pancreas Carcinoma Hereditary Pancreatic Cancer Hereditary Pancreatic Carcinoma PNCA Pancreatic Cancer, Susceptibility To Carcinoma Of Head Of Pancreas Pancreatic Neoplasms Pancreatic Tumors Cancer, Pancreatic Cancer Of Pancreas Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Multiple Sclerosis	MS Multiple Sclerosis, Susceptibility To Disseminated Sclerosis Multiple Sclerosis, Disease Progression, Modifier Of Insular Sclerosis Multiple Sclerosis Modifier Of Disease Progression Multiple Sclerosis, Susceptibility To 1 Multiple Sclerosis, Susceptibility To, 1 Multiple Sclerosis 1 Generalized Multiple Sclerosis Multiple Sclerosis Variant Multiple Sclerosis Susceptibility To Cerebrospinal Sclerosis Generalised Multiple Sclerosis Ms - [Multiple Sclerosis] Disseminated Cerebrospinal Sclerosis Disseminated Multiple Sclerosis Disseminated Nervous System Myelosclerosis Multiple Cerebrospinal Sclerosis Multiple Combined Sclerosis Multiple Sclerosis Generalised Disseminated Brain Sclerosis Disseminated Spinal Sclerosis Insular Brain Sclerosis Miliary Brain Sclerosis Multiple Combined Sclerosis Of Spinal Cord Multiple Ascending Sclerosis Multiple Brain Sclerosis Multiple Sclerosis Of Brain Stem Multiple Sclerosis Of The Brain Stem Multiple Sclerosis Of Cord Sclérose En Plaques Plaque Sclerosis Multiple Sclerosis Of The Spinal Cord
Diamond-Blackfan Anemia 5	DBA5 Rpl35a-Related Diamond-Blackfan Anemia Anemia, Diamond-Blackfan, Type 5
Vaginitis	Infective Vaginitis Inflammation Of Vagina Colpitis Vaginal Inflammation Vaginitis Nos
Bacterial Vaginosis	Vaginosis, Bacterial
Rheumatoid Arthritis	RA Arthritis, Rheumatoid Rheumatoid Arthritis, Susceptibility To Arthritis Or Polyarthritis, Rheumatic Atrophic Arthritis Rheumatism Arthritis Rheumatoid Polyarthritis
Trichomoniasis	Trichomonas Infection Trichomonas Infections Disease Due To Trichomonadidae Infection By Trichomonas Trichomonadosis Trichomonas Pruritus Trichomonosis Tricomoniasis
Vitreoretinopathy, Neovascular Inflammatory	Proliferative Vitreoretinopathy Adniv Autosomal Dominant Neovascular Inflammatory Vitreoretinopathy VRNI Pvr Neovascular Inflammatory Vitreoretinopathy Vitreoretinopathy, Neovascular Inflammatory, Autosomal Dominant Retinitis Proliferans Neovascular Inflammatory Vitreoretinopathy Autosomal Dominant Vitreoretinopathy Proliferative Vitreoretinopathy, Proliferative Proliferative Vitreo-Retinopathy
Systemic Lupus Erythematosus	Lupus Nephritis SLE Disseminated Lupus Erythematosus Systemic Lupus Erythematosus, Susceptibility To Lupus Erythematosus, Systemic Lupus Nephritis, Susceptibility To Libman-Sacks Disease Systemic Lupus Erythematosus Susceptibility To Sle - Lupus Erythematosus, Systemic Le Syndrome Lupus Lupus Erythematosus Systemic Lupus Erythematosus, Systemic, Susceptibility To Lupus Vulgaris Lupus Erythematosus, Discoid Lupus Erythematosus Systemic Lupus Erythematosus Nos Sle - [Systemic Lupus Erythematosus]
Mycobacterium Tuberculosis 1	Tuberculosis Tuberculoma Tuberculosis, Susceptibility To Mycobacterium Tuberculosis, Susceptibility To, 1 Mtbs1 TB
Bacterial Infectious Disease	Bacterial Infections Bacterial Infection Nos Disease Caused By Bacteria Bacterial Disease Or Disorder
Vaginal Disease	Vaginal Diseases
Sarcoidosis 1	Sarcoidosis Boeck Sarcoid Besnier-Boeck-Schaumann Disease SS1 Sarcoidosis, Susceptibility To, 1 Lymphogranulomatosis Hodgkin Disease Boeck'S Disease Boeck'S Sarcoid Schaumann'S Disease Or Syndrome Hutchinson-Boeck Disease Or Syndrome
Asthma	Chronic Obstructive Asthma Asthma, Diminished Response To Antileukotriene Treatment In Bronchial Hyperreactivity Asthma, Susceptibility To Asthma, Bronchial Asthma, Protection Against Asthma, Nocturnal, Susceptibility To Nocturnal Asthma Asthma-Related Traits Asthma-Related Traits, Susceptibility To Asthma, Nocturnal Chronic Obstructive Asthma With Acute Exacerbation Chronic Obstructive Asthma With Status Asthmaticus Exercise Induced Asthma Exercise-Induced Asthma Bronchial Asthma Asthma, Exercise-Induced Idiosyncratic Asthma Unspecified Asthma With Acute Exacerbation Asthma, Unspecified, With Stated Status Asthmaticus Status Asthmaticus Nos Acute Severe Asthma Acute Severe Bronchial Asthma Status Asthma Status Post Asthmaticus
Dermatitis, Atopic	Atopic Dermatitis Atopic Eczema Dermatitis, Atopic, Susceptibility To, 1 Atod Eczema, Atopic Dermatitis, Atopic 1 Allergic Dermatitis Atopic Neurodermatitis Besnier'S Prurigo Dermatitis, Atopic, 1 Dermatitis Atopic Eczema Besnier Prurigo
Coronavirus Infectious Disease
Inflammatory Bowel Disease	Inflammatory Bowel Diseases Bowel Disease, Inflammatory
Primary Bacterial Infectious Disease
Parasitic Protozoa Infectious Disease	Protozoan Infections Mastigophora Infectious Disease Sarcomastigophora Infectious Disease
Myeloma, Multiple	Multiple Myeloma Plasma Cell Myeloma Kahler Disease Myelomatosis Medullary Plasmacytoma Multiple Myeloma, Resistance To Myeloma Plasma Cell Dyscrasia Kahler'S Disease Multiple Myeloma, Susceptibility To Myeloma - Multiple Kahler-Bozzolo Disease Plasma Cell Myelomas MM Plasma Cell Neoplasm Primary Systemic Amyloidosis Primary Amyloidosis Immunoglobulin Deposition Disease Plasmacytic Myeloma Multiple Myelomata Multiple Myeloma Nos Multiple Myeloma Without Mention Of Remission Monostotic Plasma Cell Myeloma Mm - [Multiple Myeloma]
Duodenum Adenoma
Skin Disease	Skin Diseases Genodermatosis Abnormality Of The Skin Skin Diseases, Genetic Skin And Subcutaneous Tissue Disease Dermatologic Disorders
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Clinical Phase
Pre-clinical Phase

Clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Phase
HY-B0498	Bindarit	Inhibitor	99.59%	Phase 3
HY-152846	Flizasertib	Inhibitor	99.9%	Phase 2
HY-152293	EVT801	Inhibitor	/	Phase 1

Pre-clinical Phase

Bioactive Molecules (43)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-N0823	Lithospermic acid		99.56%	Unkown
HY-N0373	Licochalcone B		99.91%	Unkown
HY-N0330	Momordin Ic		99.78%	Unkown
HY-163897	PROTAC NCOA4 degrader-1	Inhibitor	99.75%	Unkown
HY-N5092	7-Methylcoumarin		99.93%	Unkown
HY-145801	XT2	Inhibitor	99.60%	Unkown
HY-N2358	Blumeatin		99.90%	Unkown
HY-N2082	Isorhamnetin 3-O-galactoside	Inhibitor	99.64%	Unkown
HY-149202	UT-11	Inhibitor	98.25%	Unkown
HY-N9173	Cupressuflavone		99.32%	Unkown
HY-121944	Ricinine		99.81%	Unkown
HY-N7327	Ochnaflavone	Inhibitor	98.30%	Unkown
HY-N7697B	Chitobiose dihydrochloride		99.84%	Unkown
HY-N8389	Globulol		99.74%	Unkown
HY-133019	ATX inhibitor 5	Inhibitor	99.20%	Unkown
HY-121271	Kadsurin		99.38%	Unkown
HY-122951	Eburicoic acid	Inhibitor	98.61%	Unkown
HY-N2998	Ganoderenic acid A	Inhibitor	97.93%	Unkown
HY-N7697F	Chitobiose		/	Unkown
HY-N15155	Vitexin 7-O-β-D-glucopyranoside		96.28%	Unkown
HY-106417	Limazocic	Inhibitor	/	Unkown
HY-120406	PLS-123		/	Unkown
HY-168713	LZ-007	Agonist	/	Unkown
HY-170846	FGFRs-IN-1	Inhibitor	/	Unkown
HY-172087	VDR agonist 3	Agonist	/	Unkown
HY-172258	5-HT2B antagonist-2	Inhibitor	/	Unkown
HY-178015	THR-β agonist 11	Agonist	/	Unkown
HY-178328	VDR agonist 4		/	Unkown
HY-179613	D-Leucine amide-CDDO-Me-HMP		/	Unkown
HY-180765	Colchicine-O-CO-Enyl(Me)-Enyl-Enyl(Me)-Enyl-1,3,3-trimethylcyclohex-1-ene	Activator	/	Unkown
HY-182287	PRDX1-IN-4		/	Unkown
HY-N0373R	Licochalcone B (Standard)		/	Unkown
HY-N12016	Fulvotomentoside B		/	Unkown
HY-N3315	Massonianoside B		/	Unkown
HY-P11264	Cyclic peptide P1-1		/	Unkown
HY-RS02102	CCL4 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS02103	CCL4L1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS02104	CCL4L2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-121944S	Ricinine-d3		/	Unkown
HY-168629	FXR agonist 9	Inhibitor	/	Unkown
HY-174752	Human CCL4L1 mRNA		/	Unkown
HY-RS16594	Ccl4 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS23028	Ccl4 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	CCL4	MGD	MGI:98261
Rattus norvegicus	CCL4	RGD	RGD:620441