TMEM254 - transmembrane protein 254 Gene
Also Known as C10orf57; bA369J21.6
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 80195
Summary
Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in skin (RPKM 17.6), prostate (RPKM 13.9) and 25 other tissues.
TMEM254 Products (9)
| mRNA | Protein | Name |
|---|---|---|
| NM_001270367.1 | NP_001257296.1 | transmembrane protein 254 isoform 2 |
| NM_001270368.1 | NP_001257297.1 | transmembrane protein 254 isoform 3 |
| NM_001270369.1 | NP_001257298.1 | transmembrane protein 254 isoform 3 |
| NM_001270370.2 | NP_001257299.1 | transmembrane protein 254 isoform 4 |
| NM_001270371.2 | NP_001257300.1 | transmembrane protein 254 isoform 5 |
| NM_001270372.2 | NP_001257301.1 | transmembrane protein 254 isoform 6 |
| NM_001270373.2 | NP_001257302.1 | transmembrane protein 254 isoform 6 |
| NM_001270374.2 | NP_001257303.1 | transmembrane protein 254 isoform 7 |
| NM_025125.4 | NP_079401.2 | transmembrane protein 254 isoform 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
32296183 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
TMEM254 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
TMEM254 | Q8TBM7 | RETREG3 | Homo sapiens | Q86VR2 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | RETREG3 | Homo sapiens | Q86VR2 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | TMEM237 | Homo sapiens | Q96Q45-2 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | TMEM237 | Homo sapiens | Q96Q45-2 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | TMEM237 | Homo sapiens | Q96Q45-2 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | ARL13B | Homo sapiens | Q3SXY8 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | ARL13B | Homo sapiens | Q3SXY8 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | TMED8 | Homo sapiens | Q6PL24 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | TMED8 | Homo sapiens | Q6PL24 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | GPX8 | Homo sapiens | Q8TED1 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | GPX8 | Homo sapiens | Q8TED1 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | GPX8 | Homo sapiens | Q8TED1 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | MFF | Homo sapiens | Q9GZY8-5 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | MFF | Homo sapiens | Q9GZY8-5 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | MFF | Homo sapiens | Q9GZY8-5 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | STOM | Homo sapiens | P27105 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | STOM | Homo sapiens | P27105 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | FNDC9 | Homo sapiens | Q8TBE3 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | FNDC9 | Homo sapiens | Q8TBE3 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | PLP1 | Homo sapiens | P60201-2 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | PLP1 | Homo sapiens | P60201-2 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | CD74 | Homo sapiens | P04233-2 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | CD74 | Homo sapiens | P04233-2 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | ATP6V0E1 | Homo sapiens | O15342 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | ATP6V0E1 | Homo sapiens | O15342 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | AQP6 | Homo sapiens | Q13520 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | AQP6 | Homo sapiens | Q13520 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | GPR152 | Homo sapiens | Q8TDT2 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | GPR152 | Homo sapiens | Q8TDT2 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | GPR152 | Homo sapiens | Q8TDT2 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | LEUTX | Homo sapiens | A8MZ59 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | LEUTX | Homo sapiens | A8MZ59 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | IL3RA | Homo sapiens | P26951 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | IL3RA | Homo sapiens | P26951 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | CPLX4 | Homo sapiens | Q7Z7G2 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | CPLX4 | Homo sapiens | Q7Z7G2 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | FAM209A | Homo sapiens | Q5JX71 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | FAM209A | Homo sapiens | Q5JX71 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | ELOVL4 | Homo sapiens | Q9GZR5 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | ELOVL4 | Homo sapiens | Q9GZR5 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | ELOVL4 | Homo sapiens | Q9GZR5 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | PAGE1 | Homo sapiens | O75459 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | PAGE1 | Homo sapiens | O75459 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | CERS4 | Homo sapiens | Q9HA82 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | CERS4 | Homo sapiens | Q9HA82 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | CERS4 | Homo sapiens | Q9HA82 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | LHFPL5 | Homo sapiens | Q8TAF8 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | LHFPL5 | Homo sapiens | Q8TAF8 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | SEC11C | Homo sapiens | Q9BY50 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | SEC11C | Homo sapiens | Q9BY50 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | SEC11C | Homo sapiens | Q9BY50 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | IFNGR2 | Homo sapiens | P38484 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | IFNGR2 | Homo sapiens | P38484 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | EBP | Homo sapiens | Q15125 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | EBP | Homo sapiens | Q15125 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | SAR1A | Homo sapiens | Q9NR31 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | SAR1A | Homo sapiens | Q9NR31 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | SAR1A | Homo sapiens | Q9NR31 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | TMEM45B | Homo sapiens | Q96B21 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | TMEM45B | Homo sapiens | Q96B21 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | TMEM45B | Homo sapiens | Q96B21 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | MTIF3 | Homo sapiens | Q9H2K0 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | MTIF3 | Homo sapiens | Q9H2K0 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | MTIF3 | Homo sapiens | Q9H2K0 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | SYT1 | Homo sapiens | P21579 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | MMGT1 | Homo sapiens | Q8N4V1 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | TMX2 | Homo sapiens | Q9Y320 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | TMX2 | Homo sapiens | Q9Y320 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | TMX2 | Homo sapiens | Q9Y320 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | BIK | Homo sapiens | Q13323 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | BIK | Homo sapiens | Q13323 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | STX1A | Homo sapiens | Q16623 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | STX1A | Homo sapiens | Q16623 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | FKBP8 | Homo sapiens | Q14318 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | FKBP8 | Homo sapiens | Q14318 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | TMEM51 | Homo sapiens | Q9NW97 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | TMEM51 | Homo sapiens | Q9NW97 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | TMEM51 | Homo sapiens | Q9NW97 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | BCL2L13 | Homo sapiens | Q9BXK5 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | BCL2L13 | Homo sapiens | Q9BXK5 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | BCL2L13 | Homo sapiens | Q9BXK5 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | REEP4 | Homo sapiens | Q9H6H4 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | REEP4 | Homo sapiens | Q9H6H4 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | REEP4 | Homo sapiens | Q9H6H4 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | CD79A | Homo sapiens | P11912 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | CD79A | Homo sapiens | P11912 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | TMEM14B | Homo sapiens | Q9NUH8 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | TMEM14B | Homo sapiens | Q9NUH8 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | TMEM14B | Homo sapiens | Q9NUH8 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | TMEM79 | Homo sapiens | Q9BSE2 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | TMEM79 | Homo sapiens | Q9BSE2 | 32296183 | |
|
Intra
|
TMEM254 | Q8TBM7 | TMEM79 | Homo sapiens | Q9BSE2 | 32296183 |
Cross: Cross-species interaction
Intra: Intraspecies interaction
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(10)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS14673 | TMEM154 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS14698 | TMEM214 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS14708 | TMEM245 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS14709 | TMEM25 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS14710 | TMEM252 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS14711 | TMEM258 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS14712 | TMEM259 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS16446 | TMEM251 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS19823 | Tmem25 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS26319 | Tmem25 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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