MT4 - metallothionein 4 Gene

Also Known as MT-4; MTIV; MT-IV

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84560

About MT4

Cytogenetic location: 16q13 Genomic coordinates (GRCh38): 16:56,565,073-56,568,957 (from NCBI)

This gene has 1 transcript (splice variant), 166 orthologues and 11 paralogues. Low expression observed in reference dataset.

Summary

Predicted to enable metal ion binding activity. Predicted to be involved in cellular response to metal ion; cellular zinc ion homeostasis; and detoxification of copper ion. Predicted to act upstream of or within cellular metal ion homeostasis. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

MT4 Products (1)

mRNA Protein Name
NM_032935.3 NP_116324.2 metallothionein-4

MT4 Protein Structure

Metallothio

Metallothio: Metallothionein (1 - 62)

  • 0
  • 62 a.a.
Protein Preferred Names Protein Names

metallothionein-4

  • metallothionein-IV

Related Diseases

Diseases Alias
Cortical Thymoma

  • Polygonal Cell Thymoma

  • Thymoma, Cortical

  • Thymoma, Type B2
Deficiency Anemia

  • Anemia

  • Deficiency Anemias

  • Anaemia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-50101A Mavorixafor trihydrochloride 99.75% Yes
HY-50101 Mavorixafor 99.72% Yes
HY-50101C Mavorixafor hydrochloride 99.64% Unkown

Clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Phase
HY-177098 Lepetegravir Inhibitor / Phase 3
HY-N0842 Bevirimat Inhibitor 99.82% Phase 2
HY-15355 Loviride Inhibitor 99.59% Phase 2
HY-12108 S 1360 Inhibitor / Phase 2

Pre-clinical Phase

Bioactive Molecules (33)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-128595 MT-4 Inhibitor 99.84% Unkown
HY-N16050 Ethyl salvianolate A Inhibitor 91.38% Unkown
HY-135856 SARS-CoV-IN-2 Inhibitor 98.66% Unkown
HY-135858 SARS-CoV-IN-3 Inhibitor 99.36% Unkown
HY-137309 4-Deoxy-4α-phorbol / Unkown
HY-146090 HIV-1 inhibitor-33 Inhibitor / Unkown
HY-10891 HIV-1 inhibitor-61 Inhibitor / Unkown
HY-116240 2′,3′-Dideoxy-5-ethyluridine / Unkown
HY-120812 HIV-IN-11 Inhibitor / Unkown
HY-122229 GS-9822 Inhibitor / Unkown
HY-125810 4'-Ethynyl-2'-deoxyadenosine Inhibitor / Unkown
HY-144714 HIV-1 inhibitor-18 Inhibitor / Unkown
HY-144715 HIV-1 inhibitor-17 Inhibitor / Unkown
HY-146015 HIV-1 inhibitor-21 Inhibitor / Unkown
HY-146019 HIV-1 inhibitor-24 Inhibitor / Unkown
HY-146019A HIV-1 inhibitor-25 Inhibitor / Unkown
HY-146091 HIV-1 inhibitor-34 Inhibitor / Unkown
HY-146352 HIV-1 inhibitor-28 Inhibitor / Unkown
HY-146353 HIV-1 inhibitor-29 Inhibitor / Unkown
HY-147723 HIV-1 inhibitor-39 Inhibitor / Unkown
HY-149866 HIV-1 inhibitor-58 Inhibitor / Unkown
HY-152539 HIV-1 inhibitor-54 Inhibitor / Unkown
HY-153583 HDAC8-IN-4 Inhibitor / Unkown
HY-181737 E3 Ligase Ligand-linker Conjugate 225 / Unkown
HY-N12260 Benanomicin A Inhibitor / Unkown
HY-RS08745 MT4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-111147 RDEA-427 Inhibitor / Unkown
HY-181034 NNRT-IN-15 Inhibitor / Unkown
HY-182497 U 95133 Inhibitor / Unkown
HY-N11288 Methyl salvionolate A Inhibitor / Unkown
HY-RS19301 Mt4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25792 Mt4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-18666 D77 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus MT4 VGNC VGNC:31713
Macaca mulatta MT4 VGNC VGNC:99525
Canis familiaris MT4 VGNC VGNC:52145
Rattus norvegicus MT4 RGD RGD:1565500
Mus musculus MT4 MGD MGI:99692
Others MT4 NCBI