HDAC-IN-106
HDAC-IN-106 is a competitive HDAC inhibitor with an IC50 of 22.9 nM against Pa-HDAC. HDAC-IN-106 can be used for research on southern corn rust and soybean rust.
For research use only. We do not sell to patients.
- Formula: C20H17F3N4O5S
- Molecular Weight:482.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
HDAC-IN-106 (Compound 9q) (0-35 nM) is a competitive inhibitor of Pa-HDAC with an IC50 of 22.9 nM and a Ki of 24.95 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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Molecular Weight 482.43
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Formula C20H17F3N4O5S
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SMILES
O=C(NC/C(C1=CC=C(S(=O)(C)=O)C=C1)=N\OC)C2=CC=C(C3=NOC(C(F)(F)F)=N3)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)