FUB 349
FUB 349 (Compound 8) is a selective Aromatase inhibitor with an IC50 of 12 μM. FUB 349 is also a H3 receptor antagonist with Kis of 12 and 2.1 nM for rH3R and hH3R, respectively. FUB 349 can be used for neurological diseases such as cognitive impairment research.
For research use only. We do not sell to patients.
- CAS No.: 184023-52-7
- Formula: C13H16N2
- Molecular Weight:200.28
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All Histamine Receptor Isoforms
More
Biological Activity
|
Aromatase 50 μM (IC50) |
human H3 receptor 2.1 nM (Ki) |
rat H3 receptor 12 nM (Ki) |
Chemical Information
-
CAS No. 184023-52-7
-
Molecular Weight 200.28
-
Formula C13H16N2
-
SMILES
C1(CCCCC2=CC=CC=C2)=CN=CN1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Karjalainen A, et al. Synthesis of new potent and selective aromatase inhibitors based on long-chained diarylalkylimidazole and diarylalkyltriazole molecule skeletons. Eur J Pharm Sci. 2000 Aug;11(2):109-31. [Content Brief]
[2]. Ligneau X, et al. Distinct pharmacology of rat and human histamine H(3) receptors: role of two amino acids in the third transmembrane domain. Br J Pharmacol. 2000 Dec;131(7):1247-50. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
FUB 349 Related Classifications
HY-123278 Related Classifications
Powered by Bioz