Ac-IETD-AFC
Based on 1 publication(s) in Google Scholar
Ac-IETD-AFC is a fluorogenic substrate of caspase-8, caspase-3, caspase-10, and granzyme B.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.28%
- CAS 番号: 211990-57-7
- 分子式: C31H38F3N5O12
- 分子量:729.65
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保管条件:
Sealed storage, away from moisture and light.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 Ac-IETD-AFC
MoreCaspase アイソフォーム固有の製品をすべて表示
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生物活性
500
380
化学情報
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CAS 番号 211990-57-7
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性状 Solid
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分子量 729.65
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分子式 C31H38F3N5O12
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Color White to off-white
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Sealed storage, away from moisture and light
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (1)
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Journal Impact Factor
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Most Recent
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Genes (Basel)
Characterization of the Apoptotic and Antimicrobial Activities of Two Initiator Caspases of Sea Cucumber Apostichopus japonicus. [Abstract]2024 Apr 25;15(5):540. PMID: 38790170
溶剤 & 溶解度
DMSO : 125 mg/mL (171.32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : < 0.1 mg/mL (insoluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. [1]Kazimierz Weglarczyk, et al. Caspase-8 activation precedes alterations of mitochondrial membrane potential during monocyte apoptosis induced by phagocytosis and killing of Staphylococcus aureus. Infect Immun. 2004 May;72(5):2590-7. [Content Brief]
[2]. Przemysław Reszka, et al. Synthesis, enzymatic evaluation, and docking studies of fluorogenic caspase 8 tetrapeptide substrates. ChemMedChem. 2010 Jan;5(1):103-17. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3705 mL | 6.8526 mL | 13.7052 mL | 34.2630 mL |
| 5 mM | 0.2741 mL | 1.3705 mL | 2.7410 mL | 6.8526 mL | |
| 10 mM | 0.1371 mL | 0.6853 mL | 1.3705 mL | 3.4263 mL | |
| 15 mM | 0.0914 mL | 0.4568 mL | 0.9137 mL | 2.2842 mL | |
| 20 mM | 0.0685 mL | 0.3426 mL | 0.6853 mL | 1.7132 mL | |
| 25 mM | 0.0548 mL | 0.2741 mL | 0.5482 mL | 1.3705 mL | |
| 30 mM | 0.0457 mL | 0.2284 mL | 0.4568 mL | 1.1421 mL | |
| 40 mM | 0.0343 mL | 0.1713 mL | 0.3426 mL | 0.8566 mL | |
| 50 mM | 0.0274 mL | 0.1371 mL | 0.2741 mL | 0.6853 mL | |
| 60 mM | 0.0228 mL | 0.1142 mL | 0.2284 mL | 0.5711 mL | |
| 80 mM | 0.0171 mL | 0.0857 mL | 0.1713 mL | 0.4283 mL | |
| 100 mM | 0.0137 mL | 0.0685 mL | 0.1371 mL | 0.3426 mL |
Ac-IETD-AFC 関連分類
HY-P1169 関連分類
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