AL-LAD
AL-LAD is a 5-HT2A receptor ligand with rat Ki values of 8.1 nM and 3.4 nM. AL-LAD mediates behavioral responses characteristic of serotonergic psychedelics. AL-LAD induces the head-twitch response in male C57BL/6J mice in an inverted-U-shaped dose-dependent manner. AL-LAD exhibits LSD-like behavioral effects in male C57BL/6J mice.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 65527-61-9
- 分子式: C22H27N3O
- 分子量:349.47
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
IC50 & Target
[1]|
5-HT2A Receptor 8.1 nM (Ki) |
5-HT2A Receptor 3.4 nM (Ki) |
体外実験
AL-LAD exhibits high affinity for 5-HT2A receptors in rat frontal cortex homogenates, with Ki values of 8.1 nM (vs. [3H]ketanserin) and 3.4 nM (vs. [125I]-R-DOI)[1].
AL-LAD binds to D1 and D2 dopaminergic receptors in rat tissue homogenates with K0.5 values of 189 nM and 12.3 nM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:C57BL/6J (male, 6−8 weeks old)[1]
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Dosage:25 µg/kg; 50 µg/kg; 100 µg/kg; 200 µg/kg; 400 µg/kg
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Administration:i.p.; single dose
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Result:Dose-dependently induced HTR with an inverted-U-shaped response; maximal response occurred at 200 μg/kg.
化学情報
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CAS 番号 65527-61-9
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分子量 349.47
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分子式 C22H27N3O
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SMILES
[H][C@@]1(CC2=CNC3=CC=CC4=C23)C4=C[C@H](CN1CC=C)C(N(CC)CC)=O
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別名
6-Allyl-6-nor-LSD
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
AL-LAD 関連分類
HY-W743888 関連分類
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