製品番号: HY-N5064

Bacoside A3

(別名: バコシド A3)

1 Cited Publications

カスタマーレビュー

Based on 1 publication(s) in Google Scholar

Bacoside A3 is a triterpenoid saponin isolated from Bacopa monnieri. Bacoside A3 has neuroprotective activity, downregulating β-amyloid-induced inflammatory responses and inhibiting neuronal apoptosis. Bacoside A3 can be used in the study of Alzheimer's disease.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

純度: 99.85%
CAS 番号: 157408-08-7
分子式: C₄₇H₇₆O₁₈
分子量:929.10

保管条件:

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Bacoside A3 構造式

CAS 番号: 157408-08-7

容量

価格（税別）

在庫状況

数量

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

NO Synthase アイソフォーム固有の製品をすべて表示 :

COX アイソフォーム固有の製品をすべて表示 :

体外実験

Bacoside A3 (0.5-5 μM; 24 h) prevents β-amyloid (10 μM)-mediated growth inhibition of U87MG cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis^[2]

Cell Line:

U87MG cells
Concentration:

0.5, 1, 1.5, 2.5 and 5 μM
Incubation Time:

24 h
Result:

Inhibited the formation of iNOS mediated by β-amyloid in U87MG cells in a dose-dependent manner and completely alleviated the effect of β-amyloid on iNOS synthesis at a dose of 5 μM.

RT-PCR^[2]

Cell Line:

U87MG cells
Concentration:

0.5, 1, 1.5, 2.5 and 5 μM
Incubation Time:

24 h
Result:

Inhibited overexpression of COX-2 mRNA, and the inhibition level of COX-2 level in U87MG cells at a dose of 5 μM is close to that of the control group.

化学情報

CAS 番号 157408-08-7
性状 Solid
分子量 929.10
分子式 C₄₇H₇₆O₁₈
Color White to off-white
SMILES

C[C@]12[C@@]34[C@@](CC[C@]1([H])[C@@]5([C@@](C(C)([C@@H](O[C@@]6([H])[C@@H]([C@H]([C@H](O)[C@@H](CO)O6)O[C@]7([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]7O)CO)O[C@]8([H])O[C@@H](CO)[C@H](O)[C@H]8O)CC5)C)([H])CC2)C)([H])[C@]9([H])[C@@](OC4)(O[C@@H](/C=C(C)/C)C[C@@]9(O)C)C3
別名

バコシド A3
Structure Classification
- Terpenoids
- Triterpenes
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Publications (1)

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Journal Impact Factor

Int J Mol Sci

From Tradition to Translation: A Critical Appraisal of Bacopa monnieri for Neuroprotection from Preclinical and Clinical Perspectives and Challenges in Utilization. [Abstract]

2026 Jun 17;27(12):5488. PMID: 42353204

溶剤 & 溶解度

体外:

DMSO : 100 mg/mL (107.63 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

1.0763 mL

5.3816 mL

10.7631 mL

5 mM

0.2153 mL

1.0763 mL

2.1526 mL

10 mM

0.1076 mL

0.5382 mL

1.0763 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (278 KB)
SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Vini C Sekhar, et al. Insights Into the Molecular Aspects of Neuroprotective Bacoside A and Bacopaside I. Curr Neuropharmacol. 2019;17(5):438-446. [Content Brief]

[2]. Bai Q, et al. Isolation and neuronal apoptosis inhibitory property of bacoside‐A3 via downregulation of β‐amyloid induced inflammatory response[J]. Biotechnology and applied biochemistry, 2022, 69(2): 726-734. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	1.0763 mL	5.3816 mL	10.7631 mL	26.9078 mL
	5 mM	0.2153 mL	1.0763 mL	2.1526 mL	5.3816 mL
	10 mM	0.1076 mL	0.5382 mL	1.0763 mL	2.6908 mL
	15 mM	0.0718 mL	0.3588 mL	0.7175 mL	1.7939 mL
	20 mM	0.0538 mL	0.2691 mL	0.5382 mL	1.3454 mL
	25 mM	0.0431 mL	0.2153 mL	0.4305 mL	1.0763 mL
	30 mM	0.0359 mL	0.1794 mL	0.3588 mL	0.8969 mL
	40 mM	0.0269 mL	0.1345 mL	0.2691 mL	0.6727 mL
	50 mM	0.0215 mL	0.1076 mL	0.2153 mL	0.5382 mL
	60 mM	0.0179 mL	0.0897 mL	0.1794 mL	0.4485 mL
	80 mM	0.0135 mL	0.0673 mL	0.1345 mL	0.3363 mL
	100 mM	0.0108 mL	0.0538 mL	0.1076 mL	0.2691 mL

Keywords

Bacoside A3

1 Cited Publications

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Bacoside A3

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MedChemExpress（MCE）の使用を引用している文献 Bacoside A3

NO Synthase アイソフォーム固有の製品をすべて表示

COX アイソフォーム固有の製品をすべて表示

生物活性

化学情報

Publications (1)

溶剤 & 溶解度

純度とドキュメンテーション

参考文献

Help & FAQs

Complete Stock Solution Preparation Table

Bacoside A3 関連分類

HY-N5064 関連分類