Dimetridazole-d3
Based on 1 publication(s) in Google Scholar
Dimetridazole-d3 (1,2-Dimethyl-5-nitroimidazole-d3) is a deuterium labeled Dimetridazole (HY-B1244). Dimetridazole is a nitroimidazole antibiotic. Dimetridazole inhibits protein synthesis in cultures of Campylobacter jejuni. Dimetridazole is genotoxic. Dimetridazole can be used in the research of protozoal and bacterial infections.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.78%
- CAS 番号: 64678-69-9
- 分子式: C5H4D3N3O2
- 分子量:144.15
-
保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
-
溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 Dimetridazole-d3
MoreAntibiotic アイソフォーム固有の製品をすべて表示
MoreParasite アイソフォーム固有の製品をすべて表示
More
生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
-
CAS 番号 64678-69-9
-
非標識Cas 551-92-8
-
性状 Solid
-
分子量 144.15
-
分子式 C5H4D3N3O2
-
Color White to off-white
-
SMILES
O=[N+](C1=CN=C(C)N1C([2H])([2H])[2H])[O-]
-
別名
1,2-Dimethyl-5-nitroimidazole-d3; ジメトリダゾール-d3
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
-
Journal Impact Factor
-
Most Recent
-
Food Addit Contam Part B Surveill
2025 Jan 29:1-12. PMID: 39877978
溶剤 & 溶解度
DMSO : 50 mg/mL (346.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (279 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
取扱説明書 (2659 KB)
参考文献
[1]. Zaghdoudi M, et al. Direct and indirect electrochemical reduction prior to a biological treatment for dimetridazoleremoval. J Hazard Mater. 2017 Aug 5;335:10-17. [Content Brief]
[2]. Fernie DS, et al. The effect of the nitroimidazole drug dimetridazole on microaerophilic campylobacters. J Med Microbiol. 1977 May;10(2):233-40. [Content Brief]
[3]. Jokipii L, et al. Comparative evaluation of the 2-methyl-5-nitroimidazole compounds dimetridazole, metronidazole, secnidazole, ornidazole, tinidazole, carnidazole, and panidazole against Bacteroides fragilis and other bacteria of the Bacteroides fragilis group. Antimicrob Agents Chemother. 1985 Oct;28(4):561-4. [Content Brief]
[4]. Ré JL, et al. Evaluation of the genotoxic activity of metronidazole and dimetridazole in human lymphocytes by the comet assay. Mutat Res. 1997 Apr 29;375(2):147-55. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.9372 mL | 34.6861 mL | 69.3722 mL | 173.4305 mL |
| 5 mM | 1.3874 mL | 6.9372 mL | 13.8744 mL | 34.6861 mL | |
| 10 mM | 0.6937 mL | 3.4686 mL | 6.9372 mL | 17.3430 mL | |
| 15 mM | 0.4625 mL | 2.3124 mL | 4.6248 mL | 11.5620 mL | |
| 20 mM | 0.3469 mL | 1.7343 mL | 3.4686 mL | 8.6715 mL | |
| 25 mM | 0.2775 mL | 1.3874 mL | 2.7749 mL | 6.9372 mL | |
| 30 mM | 0.2312 mL | 1.1562 mL | 2.3124 mL | 5.7810 mL | |
| 40 mM | 0.1734 mL | 0.8672 mL | 1.7343 mL | 4.3358 mL | |
| 50 mM | 0.1387 mL | 0.6937 mL | 1.3874 mL | 3.4686 mL | |
| 60 mM | 0.1156 mL | 0.5781 mL | 1.1562 mL | 2.8905 mL | |
| 80 mM | 0.0867 mL | 0.4336 mL | 0.8672 mL | 2.1679 mL | |
| 100 mM | 0.0694 mL | 0.3469 mL | 0.6937 mL | 1.7343 mL |
Dimetridazole-d3 関連分類
HY-B1244S 関連分類
Powered by Bioz