DPQZ
DPQZ is an anti-tubulin agent that inhibits cell separation and induces cell cycle arrest at the G2/M phase. In addition, DPQZ induces caspase-dependent apoptosis of HSC-3 cells by inhibiting Ras/Raf and activating MAP kinase. DPQZ can be used in the study of oral cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1431362-93-4
- 分子式: C20H17N3O
- 分子量:315.37
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-15 | IC50 |
0.46 μM
Compound: 14
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Cytotoxicity against human HCT15 cells measured after 2 days by MTT assay
Cytotoxicity against human HCT15 cells measured after 2 days by MTT assay
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[PMID: 26334499] |
| HeLa | IC50 |
0.05 μM
Compound: 14
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Cytotoxicity against human HeLa cells measured after 2 days by MTT assay
Cytotoxicity against human HeLa cells measured after 2 days by MTT assay
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[PMID: 26334499] |
| T47D | IC50 |
>50 μM
Compound: 14
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Cytotoxicity against human T47D cells measured after 2 days by MTT assay
Cytotoxicity against human T47D cells measured after 2 days by MTT assay
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[PMID: 26334499] |
化学情報
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CAS 番号 1431362-93-4
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分子量 315.37
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分子式 C20H17N3O
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SMILES
O=C1N=C(C2=C3C=CC=CC3=CC=C2)NC4=CC=C(N(C)C)C=C14
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
DPQZ 関連分類
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