FOXP3 - forkhead box P3 Gene

Also Known as JM2; AIID; IPEX; PIDX; XPID; DIETER

生物種: Homo sapiens

遺伝子タイプ: protein coding

遺伝子ID: 50943

About FOXP3

Cytogenetic location: Xp11.23 Genomic coordinates (GRCh38): X:49,250,438-49,264,710 (from NCBI)

This gene has 9 transcripts (splice variants), 102 orthologues, 42 paralogues and is associated with 3 phenotypes. Ubiquitous expression in appendix (RPKM 2.2), lymph node (RPKM 1.8) and 25 other tissues.

Summary

The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

FOXP3 Products (2)

mRNA	Protein	Name
NM_001114377.2	NP_001107849.1	forkhead box protein P3 isoform b
NM_014009.4	NP_054728.2	forkhead box protein P3 isoform a

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	参考文献	由来
enables DNA binding	IMP IMP: Inferred from mutant phenotype	21458306	GOA
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IDA IDA: Inferred from direct assay	19276356	GOA
enables DNA-binding transcription factor activity	IDA IDA: Inferred from direct assay	11483607	GOA
enables NFAT protein binding	IPI IPI: Inferred from physical interaction	16873067	GOA
enables histone acetyltransferase binding	IPI IPI: Inferred from physical interaction	17360565	GOA
enables histone deacetylase binding	IPI IPI: Inferred from physical interaction	17360565	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	16652169	GOA
enables protein homodimerization activity	IDA IDA: Inferred from direct assay	21458306	GOA
enables protein homodimerization activity	IPI IPI: Inferred from physical interaction	16920951	GOA
enables sequence-specific DNA binding	IDA IDA: Inferred from direct assay	11483607	GOA
enables sequence-specific double-stranded DNA binding	IDA IDA: Inferred from direct assay	28473536	GOA

Biological Process GO Annotation	Evidence	参考文献	由来
involved in T cell activation	IDA IDA: Inferred from direct assay	15466453	GOA
involved in negative regulation of CREB transcription factor activity	IDA IDA: Inferred from direct assay	16652169	GOA
involved in negative regulation of DNA-binding transcription factor activity	IDA IDA: Inferred from direct assay	16873067	GOA
involved in negative regulation of DNA-templated transcription	IDA IDA: Inferred from direct assay	11483607	GOA
involved in negative regulation of DNA-templated transcription	IMP IMP: Inferred from mutant phenotype	21458306	GOA
involved in negative regulation of NF-kappaB transcription factor activity	IDA IDA: Inferred from direct assay	16652169	GOA
involved in negative regulation of T cell cytokine production	IDA IDA: Inferred from direct assay	15466453	GOA
involved in negative regulation of T cell cytokine production	IMP IMP: Inferred from mutant phenotype	23169781	GOA
involved in negative regulation of T cell proliferation	IDA IDA: Inferred from direct assay	15466453	GOA
involved in negative regulation of T cell proliferation	IMP IMP: Inferred from mutant phenotype	21458306	GOA
involved in negative regulation of T-helper 17 cell differentiation	IMP IMP: Inferred from mutant phenotype	23169781	GOA
involved in negative regulation of cell population proliferation	IDA IDA: Inferred from direct assay	15652505	GOA
involved in negative regulation of cytokine production	IDA IDA: Inferred from direct assay	11483607	GOA
involved in negative regulation of immune response	IDA IDA: Inferred from direct assay	15652505	GOA
involved in negative regulation of interleukin-10 production	IDA IDA: Inferred from direct assay	15466453	GOA
involved in negative regulation of interleukin-17 production	IMP IMP: Inferred from mutant phenotype	18368049	GOA
involved in negative regulation of interleukin-2 production	IDA IDA: Inferred from direct assay	15466453	GOA
involved in negative regulation of interleukin-2 production	IMP IMP: Inferred from mutant phenotype	16873067	GOA
involved in negative regulation of interleukin-4 production	IDA IDA: Inferred from direct assay	15466453	GOA
involved in negative regulation of type II interferon production	IDA IDA: Inferred from direct assay	15466453	GOA
involved in negative regulation of type II interferon production	IMP IMP: Inferred from mutant phenotype	23169781	GOA
involved in positive regulation of DNA-templated transcription	IDA IDA: Inferred from direct assay	15466453	GOA
involved in positive regulation of DNA-templated transcription	IMP IMP: Inferred from mutant phenotype	21458306	GOA
involved in positive regulation of regulatory T cell differentiation	IDA IDA: Inferred from direct assay	30513302	GOA
involved in positive regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	19276356	GOA
involved in regulatory T cell differentiation	IDA IDA: Inferred from direct assay	32644293	GOA
involved in response to virus	IEP IEP: Inferred from expression pattern	20583921	GOA

Cellular Component GO Annotation	Evidence	参考文献	由来
located in cytoplasm	IDA IDA: Inferred from direct assay	22678915	GOA
is active in nucleus	IDA IDA: Inferred from direct assay	32644293	GOA
located in nucleus	IDA IDA: Inferred from direct assay	11483607	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FOXP3 Protein Structure

Forkhead

0
100
200
300
400
431 a.a.

Protein Preferred Names	Protein Names
forkhead box protein P3	FOXP3delta7

FOXP3 Protein-protein interaction Information

Type	タンパク質名	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	参考文献
Intra	FOXP3	Q9BZS1	PRR20C	Homo sapiens	P86479	Validated Y2H	25416956
Intra	FOXP3	Q9BZS1	PRR20C	Homo sapiens	P86479	Y2H Array	25416956
Intra	FOXP3	Q9BZS1	PRR20C	Homo sapiens	P86479	Y2H Prey Pooling	25416956
Intra	FOXP3	Q9BZS1	KRTAP8-1	Homo sapiens	Q8IUC2	Y2H Prey Pooling	32296183
Intra	FOXP3	Q9BZS1	KRTAP8-1	Homo sapiens	Q8IUC2	Y2H Array	32296183
Intra	FOXP3	Q9BZS1	RORA	Homo sapiens	P35398-4	Y2H	18354202
Intra	FOXP3	Q9BZS1	RORA	Homo sapiens	P35398-4	Anti Tag CoIP	18354202
Intra	FOXP3	Q9BZS1	ZFP90	Homo sapiens	Q8TF47-3	LexA B52 Complement	23543754
Intra	FOXP3	Q9BZS1	KRTAP6-2	Homo sapiens	Q3LI66	Y2H Prey Pooling	32296183
Intra	FOXP3	Q9BZS1	KRTAP6-2	Homo sapiens	Q3LI66	Y2H Array	32296183
Intra	FOXP3	Q9BZS1	PRR20E	Homo sapiens	P86478	Validated Y2H	25910212
Intra	FOXP3	Q9BZS1	PRR20E	Homo sapiens	P86478	Y2H Bait-Prey Pool	25910212
Intra	FOXP3	Q9BZS1	PRR20E	Homo sapiens	P86478	Y2H Array	25910212
Intra	FOXP3	Q9BZS1	PRR20D	Homo sapiens	P86480	Y2H Array	32296183
Intra	FOXP3	Q9BZS1	PRR20D	Homo sapiens	P86480	Y2H Prey Pooling	32296183
Intra	FOXP3	Q9BZS1	USP44	Homo sapiens	Q9H0E7	Confocal	32644293
Intra	FOXP3	Q9BZS1	FOSB	Homo sapiens	P53539	Y2H Array	32296183
Intra	FOXP3	Q9BZS1	FOSB	Homo sapiens	P53539	Y2H Prey Pooling	32296183
Intra	FOXP3	Q9BZS1	STUB1	Homo sapiens	Q9UNE7	Anti Bait CoIP	23973223
Intra	FOXP3	Q9BZS1	STUB1	Homo sapiens	Q9UNE7	Confocal	23973223
Intra	FOXP3	Q9BZS1	STUB1	Homo sapiens	Q9UNE7	Anti Tag CoIP	23973223
Intra	FOXP3	Q9BZS1	KRTAP3-3	Homo sapiens	Q9BYR6	Y2H Array	32296183
Intra	FOXP3	Q9BZS1	KRTAP3-3	Homo sapiens	Q9BYR6	Y2H Prey Pooling	32296183
Intra	FOXP3	Q9BZS1	EZH2	Homo sapiens	Q15910	Anti Bait CoIP	30510991
Intra	FOXP3	Q9BZS1	EZH2	Homo sapiens	Q15910	PLA	30510991
Intra	FOXP3	Q9BZS1	RBPMS	Homo sapiens	Q93062	Y2H Array	25416956
Intra	FOXP3	Q9BZS1	RBPMS	Homo sapiens	Q93062-3	Y2H Bait-Prey Pool	25910212
Intra	FOXP3	Q9BZS1	RBPMS	Homo sapiens	Q93062-3	Validated Y2H	25910212
Intra	FOXP3	Q9BZS1	RBPMS	Homo sapiens	Q93062-3	Y2H Array	25910212
Intra	FOXP3	Q9BZS1	IKZF3	Homo sapiens	Q9UKT9	Anti Bait CoIP	20676092

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant FOXP3 Proteins

製品番号	製品名	アクセッション番号	純度
HY-P71628	FOXP3 Protein, Human (His)	Q9BZS1-1 (M1-L260)	≥ 90%, as determined by reducing SDS-PAGE.

FOXP3 抗体

製品番号	製品名	アプリケーション	反応性
HY-P80135	FOXP3 Antibody (YA425)	WB, ICC/IF, FC	Human
HY-P80678	FOXP3 Antibody (YA759)	WB, IHC-P, ICC/IF, mIHC	Human, Mouse, Rat
HY-P80678A	FOXP3 Antibody (YA759)(PBS only)	WB, IHC-P, ICC/IF, mIHC	Human, Mouse, Rat
HY-P80965	FOXP3 Antibody (YA858)	WB, IHC-P	Human
HY-P84777	FOXP3 Antibody (YA4474)	IHC-P, ICC/IF, ELISA	Human, Mouse
HY-P84777A	FOXP3 Antibody (YA4474)(PBS only)	IHC-P, ICC/IF, ELISA	Human, Mouse
HY-P84778	FOXP3 Antibody (YA4475)	WB, IHC-P, FC, ELISA	Human, Mouse, Rabbit
HY-P84778A	FOXP3 Antibody (YA4475)(PBS only)	WB, IHC-P, FC, ELISA	Human, Mouse, Rabbit
HY-P85174	FoxP3 Antibody (YA4866)	WB, IHC-P, ICC/IF, ELISA	Human, Mouse
HY-P86558	FOXP3 Antibody (YA6250)	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
HY-P86750	FOXP3 Antibody (YA6442)	FC	Human
HY-P86750A	FOXP3 Antibody (YA6442)(PBS only)	FC	Human
HY-P86916	FOXP3 Antibody(YA6609)	WB, IHC-P, mIHC	Human, Mouse, Rat

関連疾患

Diseases	Alias
Immunodysregulation, Polyendocrinopathy, And Enteropathy, X-Linked	IPEX X-Linked Autoimmunity-Allergic Dysregulation Syndrome Xlaad Diarrhea, Polyendocrinopathy, Fatal Infection Syndrome, X-Linked Ipex Syndrome Insulin-Dependent Diabetes Mellitus Secretory Diarrhea Syndrome Iddm-Secretory Diarrhea Syndrome Dmsd Autoimmunity-Immunodeficiency Syndrome, X-Linked Enteropathy, Autoimmune, With Hemolytic Anemia And Polyendocrinopathy Xpid Diabetes Mellitus, Congenital Insulin-Dependent, With Fatal Secretory Diarrhea Immune Dysregulation-Polyendocrinopathy-Enteropathy-X-Linked Syndrome Polyendocrinopathy, Immune Dysfunction, And Diarrhea, X-Linked Autoimmune Enteropathy Type 1 Immunodeficiency, Polyendocrinopathy, And Enteropathy, X-Linked Immunodeficiency, Polyendocrinopathy, And Enteropathy, X-Linked, Formerly Immunodeficiency, Polyendocrinopathy, Enteropathy X-Linked Syndrome Immunodysregulation, Polyendocrinopathy And Enteropathy X-Linked Autoimmunity-Immunodeficiency Syndrome X-Linked Iddm Secretory Diarrhea Syndrome Polyendocrinopathy, Immune Dysfunction And Diarrhea X-Linked Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-Linked Syndrome Immunodeficiency Polyendocrinopathy, Enteropathy, X-Linked Syndrome X-Linked Autoimmunity-Immunodeficiency Syndrome Immunodeficiency, Polyendocrinopathy, And Enteropathy X-Linked Syndrome X-Linked Syndrome Of Polyendocrinopathy, Immune Dysfunction, And Diarrhea
Hydrops Fetalis, Nonimmune	Hydrops Fetalis Non-Immune Hydrops Fetalis NIHF Familial Non-Immune Hydrops Fetalis Hydrops Fetalis Nonimmune Idiopathic Hydrops Fetalis Hb Bart'S Hydrops Fetalis Alpha-Thalassemia Hydrops Fetalis Alpha-Thalassemia Major Hemoglobin Bart'S Hydrops Fetalis Homozygous Alpha0-Thalassemia Fetal Anasarca Fetal Hydrops Generalized Fetal Edema Hf Non-Immune Hf Non-Immune Fetal Edema Non-Immune Fetal Hydrops Hydrops Fetalis, Non-Immune Hemoglobin Bart'S Hydrops Syndrome
Pancytopenia
Deficiency Anemia	Anemia Deficiency Anemias Anaemia
Polyendocrinopathy
Multinucleated Neurons, Anhydramnios, Renal Dysplasia, Cerebellar Hypoplasia, And Hydranencephaly	MARCH Multinucleated Neurons, Anhydramnios, Renal Dysplasia, Cerebellar Hypoplasia And Hydranencephaly Multinucleated Neurons-Anhydramnios-Renal Dysplasia-Cerebellar Hypoplasia-Hydranencephaly Syndrome Hydranencephaly With Renal Aplasia-Dysplasia March Syndrome
Colitis
Tropical Spastic Paraparesis	Tropical Spastic Paraplegia Ham/Tsp Htlv-Associated Myelopathy Tropical Spastic Paralysis Htlv-1 Associated Myelopathy/Tropical Spastic Paraparesis Human T-Cell Leukemia Virus Type 1 Associated Myelopathy/Tropical Spastic Paraparesis Htlv-1-Associated Myelopathy/Tropical Spastic Paraparesis Human T-Lymphotropic Virus Type I-Associated Myelopathy/Tropical Spastic Paraparesis Human T-Lymphotropic Virus Type-1-Associated Myelopathy/Tropical Spastic Paraparesis Tsp Paraparesis Tropical Spastic Paraparesis, Tropical Spastic
Type 1 Diabetes Mellitus	Diabetes Mellitus, Insulin-Dependent Diabetes Mellitus Type 1 IDDM Type 1 Diabetes Insulin-Dependent Diabetes Mellitus T1D Juvenile-Onset Diabetes Jod Diabetes Mellitus, Type 1 Diabetes Mellitus, Insulin-Dependent-1 Type I Diabetes Mellitus Autoimmune Diabetes Juvenile Diabetes Juvenile-Onset Diabetes Mellitus Diabetes, Insulin Dependent Insulin-Dependent Diabetes Mellitus-1 Diabetes Mellitus Insulin-Dependent Diabetes Autoimmune Diabetes Mellitus, Insulin-Dependent, Susceptibility To Diabetes Mellitus, Type 1, Susceptibility To Diabetes Type 1 Type I Diabetes Diabetes, Autoimmune T1dm - [Type 1 Diabetes Mellitus] Iddm - [Insulin Dependent Diabetes Mellitus] Type 1 Iddm Juvenile Diabetes Mellitus Without Compications Idiopathic Insulin-Dependent Diabetes Mellitus Without Complications Juvenile-Onset Diabetes Mellitus Without Compications Ketosis-Prone Diabetes Mellitus Without Compications Juvenile-Onset-Type Diabetes Mellitus Without Compications
Autoimmune Polyendocrine Syndrome	Autoimmune Polyendocrinopathy Autoimmune Polyglandular Failure Autoimmune Polyglandular Syndrome Polyendocrinopathies, Autoimmune Lloyd'S Syndrome Aps Polyendocrinopathies Autoimmune Polyendocrine Autoimmunity Syndrome Lloyd Syndrome Polyglandular Autoimmune Deficiency Progressive Pluriglandular Insufficiency Pluriglandular Autoimmune Atrophy Pluriglandular Autoimmune Syndrome Thyroid-Adrenocortical Insufficiency Syndrome
Diarrhea	Diarrhoea Diarrhea Of Presumed Infectious Origin
Autoimmune Disease	Autoimmune Diseases Autoimmune Hypersensitivity Disease Hypersensitivity Reaction Type Ii Disease Type Ii Hypersensitivity Reaction Disease
Secretory Diarrhea
Lymphopenia	Lymphocytopenia
Food Allergy	Food Hypersensitivity Food Allergies Allergy Food Food Allergen-Induced Hypersensitivity
Ulcerative Colitis	Colitis Gravis Left Sided Ulcerative Colitis Left-Sided Ulcerative Colitis Idiopathic Proctocolitis Inflammatory Bowel Disease, Ulcerative Colitis Type Uc Colitis Ulcerative Colitis, Ulcerative Chronic Left-Sided Ulcerative Colitis Uc - [Ulcerative Colitis] Chronic Ulcerative Enteritis Mucosal Proctocolitis Ulcerative Mucosal Proctocolitis Left Hemicolitis
Thyroiditis	Inflammation Of Thyroid Thyroiditis Nos
Inflammatory Bowel Disease	Inflammatory Bowel Diseases Bowel Disease, Inflammatory
Omenn Syndrome	Histiocytic Medullary Reticulosis Severe Combined Immunodeficiency With Hypereosinophilia Combined Immunodeficiency With Hypereosinophilia Reticuloendotheliosis, Familial, With Eosinophilia Reticuloendotheliosis Familial With Eosinophilia Familial Reticuloendotheliosis Omenn'S Syndrome OS Malignant Histiocytosis
Immunodeficiency 41 With Lymphoproliferation And Autoimmunity	Cd25 Deficiency Immunodeficiency Due To Cd25 Deficiency IMD41 Interleukin 2 Receptor, Alpha, Deficiency Of Il2ra Deficiency Immunodeficiency 41 Interleukin-2 Receptor Alpha Chain Deficiency Interleukin 2 Receptor Alpha Deficiency Interleukin-2 Receptor, Alpha Chain, Deficiency Of Immunodeficiency, Type 41 With Lymphoproliferation And Autoimmunity
Rheumatoid Arthritis	RA Arthritis, Rheumatoid Rheumatoid Arthritis, Susceptibility To Arthritis Or Polyarthritis, Rheumatic Atrophic Arthritis Rheumatism Arthritis Rheumatoid Polyarthritis
Hypersplenism	Hypersplenia Big Spleen Syndrome Hyperfunction Of Spleen Increased Splenic Activity Spleen Metaplasia Splenic Metaplasia
Relapsing-Remitting Multiple Sclerosis	Relapsing-Remitting Ms Relapsing Remitting Multiple Sclerosis Multiple Sclerosis, Relapsing-Remitting Rrms Multiple Sclerosis Relapsing-Remitting
Syphilis	Chancre Syphilitic Chancre
Bronchiolitis Obliterans	Bronchiolitis Fibrosa Obliterans Obliterative Bronchiolitis Bronchiolitis Exudativa Bronchiolitis, Exudative
Visceral Leishmaniasis	Kala-Azar Leishmaniasis, Visceral Infection By Visceral Leishmaniasis Leishmaniasis Visceral Sahib Disease Ponos Burdwan Fever Mard El Bicha Sirkari Disease Indian Visceral Leishmaniasis Dumdum Fever Visceral Leishmaniasis Due To Leishmania Donovani
Dermatitis	Eczema Skin Inflammation Inflammatory Dermatosis
Granulomatosis With Polyangiitis	GPA Wegener Granulomatosis Wegener Granulomatosis, Formerly Midline Granulomatosis Wg, Formerly Necrotizing Respiratory Granulomatosis Wg Wegeners Granulomatosis Pauci-Immune Glomerulonephritis Associated With Granulomatosis With Polyangiitis
Leishmaniasis	Post-Kala-Azar Dermal Leishmaniasis Post Kala-Azar Dermal Leishmaniasis Post-Kala-Azar Dermal Infectious Disease By Leishmaniasis Cutaneous Leishmaniasis Kala-Azar Visceral Leishmaniasis Leishmaniasis, Cutaneous Leishmaniasis, Visceral Leishmania Leishmania Infection Leishmaniosis
Arthritis	Inflammatory Joint Disease Inflammatory Disorder Of Joint
Megacolon	Dilatation Of Colon
Thrombocytopenia	Low Platelet Count Low Platelets Decreased Platelets Platelet Dysfunction Nos
Autoimmune Hepatitis	Aih Hepatitis, Autoimmune Autoimmune Chronic Active Hepatitis Autoimmune Hepatitis With Centrilobular Necrosis Autoimmune Chronic Hepatitis Hepatitis Autoimmune
Conjunctivitis	Madras Eye Adenoviral Conjunctivitis Acute Adenoviral Follicular Conjunctivitis Inclusion Conjunctivitis Of The Adult Swimming-Pool Conjunctivitis Inflammation Of Conjunctiva Ophthalmia Acute Conjunctivitis Eye Catarrh Catarrhal Ophthalmia Koch-Weeks Conjunctivitis
Myasthenia Gravis	MG Acquired Myasthenia Autoimmune Myasthenia Gravis Erb-Goldflam Disease Mg - [Myasthenia Gravis] Myasthenia Gravis Nos Myasthenia
Rhinitis	Runny Nose
Prostatitis
Alopecia Areata	Aa Alopecia Celsi Alopecia Circumscripta Cazenave'S Vitiligo Celsus' Vitiligo Diffuse Alopecia Jonston'S Alopecia Marginal Alopecia Pseudopelade Circumscribed Alopecia Alopecia Cicatrisata Patchy Alopecia Alopecia Aa - [Alopecia Areata] Pelade
Diabetes Mellitus	Diabetes
Chagas Disease	American Trypanosomiasis Chagas' Disease Chagas' Disease With Digestive System Involvement Chagas' Disease With Nervous System Involvement Chagas' Disease With Other Organ Involvement Infection Due To Trypanosoma Cruzi South American Trypanosomiasis Chronic Chagas Disease With Digestive System Involvement
Thymoma	Primary Thymic Epithelial Neoplasm Primary Thymic Epithelial Tumor Thymus Neoplasms
Autoimmune Disease Of Eyes, Ear, Nose And Throat
Common Variable Immunodeficiency	Cvid Common Variable Agammaglobulinemia Common Variable Immune Deficiency Acquired Hypogammaglobulinemia Hypogamma-Globulinemia, Acquired Idiopathic Immunoglobulin Deficiency Primary Antibody Deficiency Primary Hypogammaglobulinemia Acquired Agammaglobulinemia Sporadic Hypogammaglobulinemia Common Variable Hypogamma-Globulinemia Immunoglobulin Deficiency, Late-Onset Common Variable Hypogammaglobulinemia Immunodeficiency, Common Variable
Autoimmune Gastritis
Mycosis Fungoides	Mycosis Fungoides Lymphoma Alibert-Bazin Syndrome Granuloma Fungoides Classic Mycosis Fungoides Mycosis Fungoides, Alibert-Bazin Type
Multiple Sclerosis	MS Multiple Sclerosis, Susceptibility To Disseminated Sclerosis Multiple Sclerosis, Disease Progression, Modifier Of Insular Sclerosis Multiple Sclerosis Modifier Of Disease Progression Multiple Sclerosis, Susceptibility To 1 Multiple Sclerosis, Susceptibility To, 1 Multiple Sclerosis 1 Generalized Multiple Sclerosis Multiple Sclerosis Variant Multiple Sclerosis Susceptibility To Cerebrospinal Sclerosis Generalised Multiple Sclerosis Ms - [Multiple Sclerosis] Disseminated Cerebrospinal Sclerosis Disseminated Multiple Sclerosis Disseminated Nervous System Myelosclerosis Multiple Cerebrospinal Sclerosis Multiple Combined Sclerosis Multiple Sclerosis Generalised Disseminated Brain Sclerosis Disseminated Spinal Sclerosis Insular Brain Sclerosis Miliary Brain Sclerosis Multiple Combined Sclerosis Of Spinal Cord Multiple Ascending Sclerosis Multiple Brain Sclerosis Multiple Sclerosis Of Brain Stem Multiple Sclerosis Of The Brain Stem Multiple Sclerosis Of Cord Sclérose En Plaques Plaque Sclerosis Multiple Sclerosis Of The Spinal Cord
Late Congenital Syphilis	Juvenile Neurosyphilis Neurosyphilis, Juvenile
Autoimmune Uveitis
Malaria	Malaria, Susceptibility To Malaria, Resistance To Malaria, Cerebral Cerebral Malaria Malaria, Severe, Susceptibility To Malaria, Severe, Resistance To Malaria, Cerebral, Susceptibility To Induced Malaria Malaria, Vivax, Protection Against Malaria, Severe Malaria, Cerebral, Reduced Risk Of Malaria, Protection Against Resistance To Malaria Due To G6pd Deficiency Malaria Due To G6pd Deficiency Malarial Encephalitis CM Malaria Cerebral Susceptibility To Malaria Acute Pernicious Fever Aestivo-Autumnal Fever Aestivo Autumnal Malaria Chagres Fever Continued Malaria Fever Estivo-Autumnal Fever Estivo-Autumnal Malaria Estivo-Autumnal Malarial Fever Falciparum Fever Malignant Tertian Fever Malignant Tertian Malaria Pernicious Intermittent Fever Pernicious Malaria Quotidian Malaria Subtertian Fever Subtertian Malaria Fever Subtertian Malignant Tertian Malaria Tropical Malaria Algid Malaria Bilious Haemoglobinuric Fever Black Water Fever Blackwater Fever Malarial Blackwater Fever Severe Malarial Falciparum West African Fever Malarial Haematinuria Haemoglobinuric Fever Haemoglobinuric Malaria Severe Plasmodium Falciparum Malaria Malarial Haemoglobinuria Malarial Haematuria Falciparum Malaria [Malignant Tertian] Malaria Tropica Malarial Shock Chagres Virus Disease Malignant Malaria Mtm - [Malignant Tertian Malaria] Tm -[Malignant Tertian Malaria] Panama Fever St - [Subtertian Malaria] Malarial Quotidian Benign Tertian Malaria Tertian Ague Vivax Fever Plasmodium Vivax Malaria Nos Btm - [Benign Tertian Malaria] Bt - [Benign Tertian Malaria] Vivax Malaria Benign Tertian Vivax Malaria Tertian Malaria Quartan Malaria Quartan Ague Quartan Fever Plasmodium Malariae Malaria Nos Quartan Malarial Malaria By Plasmodium Malariae Malariae Malaria Ovale Tertian Malaria Plasmodium Ovale Fever Malaria Fever By Plasmodium Ovale Ovale Malaria Malaria By Plasmodium Ovale Malarial Ovale Marsh Fever Remittent Congestive Fever Coastal Fever Remittent Gastric Fever Miasmatic Fever Congestive Remittent Fever Intermittent Fever Jungle Fever Paludism Cameroon Fever Ague Corsican Fever Intermittent Bilious Fever Disease Due To Plasmodiidae Malarial Fever Plasmodiosis Remittent Fever Roman Fever Malaria Fever Nos Malaria Nos Paludal Fever Clinically Diagnosed Malaria Clinically Diagnosed Malaria Without Parasitological Confirmation Congestive Fever Malarial Cachexia Marsh Cachexia Paludal Cachexia Recurrent Malaria Remittent Malaria
Fruit Allergy	Allergy To Fruit
Legume Allergy	Fabaceae Allergy
Gastroesophageal Reflux	Gastroesophageal Reflux Disease Gerd GER Gastroesophageal Reflux, Pediatric Acid Reflux Gastresophageal Reflux Gastro-Esophageal Reflux Gerd - Gastro-Esophageal Reflux Disease
Systemic Scleroderma	Scleroderma Progressive Systemic Sclerosis Systemic Sclerosis Scleroderma, Systemic Scleroderma Syndrome Dermatosclerosis Familial Progressive Scleroderma Progressive Scleroderma Scleroderma Disease Scleroderma, Localized Diffuse Scleroderma Scleroderma, Familial Progressive
Respiratory Allergy	Airway Allergy
Autoimmune Polyendocrine Syndrome Type 1	Whitaker Syndrome Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Autoimmune Polyglandular Syndrome I Polyglandular Type I Autoimmune Syndrome
Egg Allergy	Allergy To Eggs Allergies Egg Egg Hypersensitivity
Chronic Asthma
Peanut Allergy	Allergy To Peanuts Peanut Allergic Reaction Allergies Peanut Peanut Hypersensitivity
Arteriosclerosis	Arteriosclerotic Vascular Disease
Caplan'S Syndrome	Caplan Syndrome Caplan'S Disease Caplans Syndrome Rheumatoid Pneumoconiosis
Milk Allergy	Milk Allergic Reaction Milk Hypersensitivity Allergy Milk
Autoimmune Disease Of Central Nervous System
Parasitic Helminthiasis Infectious Disease	Helminthiasis Intestinal Helminthiasis Helminth Infection Helminthosis Worm Infection Worm Infections Helminth Infections Intestinal Infection Due To Class Cestoda And/Or Class Trematoda And/Or Phylum Nemata Parasitic Enteritis Metazoal Dysentery Intestinal Worms Nos
Autoimmune Disease Of Endocrine System
Autoimmune Disease Of Gastrointestinal Tract
Type 1 Diabetes Mellitus 5	Diabetes Mellitus, Insulin-Dependent, 5 Latent Autoimmune Diabetes In Adults IDDM5 Insulin-Dependent Diabetes Mellitus 5 T1D5 Lada Type 1.5 Diabetes Diabetes Mellitus, Insulin-Dependent, Type 5
Systemic Lupus Erythematosus	Lupus Nephritis SLE Disseminated Lupus Erythematosus Systemic Lupus Erythematosus, Susceptibility To Lupus Erythematosus, Systemic Lupus Nephritis, Susceptibility To Libman-Sacks Disease Systemic Lupus Erythematosus Susceptibility To Sle - Lupus Erythematosus, Systemic Le Syndrome Lupus Lupus Erythematosus Systemic Lupus Erythematosus, Systemic, Susceptibility To Lupus Vulgaris Lupus Erythematosus, Discoid Lupus Erythematosus Systemic Lupus Erythematosus Nos Sle - [Systemic Lupus Erythematosus]
Asthma	Chronic Obstructive Asthma Asthma, Diminished Response To Antileukotriene Treatment In Bronchial Hyperreactivity Asthma, Susceptibility To Asthma, Bronchial Asthma, Protection Against Asthma, Nocturnal, Susceptibility To Nocturnal Asthma Asthma-Related Traits Asthma-Related Traits, Susceptibility To Asthma, Nocturnal Chronic Obstructive Asthma With Acute Exacerbation Chronic Obstructive Asthma With Status Asthmaticus Exercise Induced Asthma Exercise-Induced Asthma Bronchial Asthma Asthma, Exercise-Induced Idiosyncratic Asthma Unspecified Asthma With Acute Exacerbation Asthma, Unspecified, With Stated Status Asthmaticus Status Asthmaticus Nos Acute Severe Asthma Acute Severe Bronchial Asthma Status Asthma Status Post Asthmaticus
Nasal Cavity Disease	Disorder Of Nasal Cavity
Autoimmune Atherosclerosis
Lymphocytic Colitis	Colitis, Lymphocytic
Autoimmune Myocarditis
T-Cell Adult Acute Lymphocytic Leukemia	Acute Adult T-Cell Leukemia-Lymphoma Adult Precursor T Lymphoblastic Leukemia Atll T-Cell Adult Acute Lymphoblastic Leukemia
Autoimmune Disease Of Musculoskeletal System
Bronchial Disease	Bronchial Diseases Bronchial Disorders Bronchial Spasm
Nose Disease	Nose Diseases Disorder Of The Nose Nasal Disorder Abnormality Of The Nose
Autoimmune Neuropathy
Glioblastoma	Glioblastoma Multiforme Gbm Adult Glioblastoma Multiforme Grade Iv Adult Astrocytic Tumor Primary Glioblastoma Multiforme Spongioblastoma Multiforme Adult Glioblastoma Primary Glioblastoma
Dermatitis, Atopic, 8	ATOD8 Atopic Dermatitis 8 Dermatitis, Atopic, Severity Of Dermatitis, Atopic, Susceptibility To, 8 Dermatitis, Atopic 8
Lymphoid Interstitial Pneumonia	Lymphocytic Interstitial Pneumonia Lip Disease Lip Diseases LIP Disease Of Lips
Primary Biliary Cholangitis	Primary Biliary Cirrhosis Biliary Liver Cirrhosis Chronic Nonsuppurative Destructive Cholangitis Familial Primary Biliary Cirrhosis Pbc Hanot Syndrome Cholestatic Cirrhosis Biliary Cirrhosis Primary Liver Cirrhosis, Biliary Hanot'S Cirrhosis Biliary Cirrhosis Pericholangiolic Biliary Cirrhosis Tannhauser-Magendantz Syndrome Hanot-Rossle Syndrome Hypertrophic Cirrhosis Todd Cirrhosis Hanot Cirrhosis Charcot Cirrhosis Mahon-Tannhauser Syndrome Toxic Cirrhosis Hypertrophic Biliary Cirrhosis Monolobular Cirrhosis Unilobar Cirrhosis Xanthomatous Biliary Cirrhosis
Trichinosis	Trichinellosis Human Trichinellosis Trichiniasis Trichinella Spiralis Infection Infection With Trichinella Trichinelliasis Trichinella Spiralis Infestation
Lung Cancer	Lung Carcinoma Non-Small Cell Lung Carcinoma Lung Cancer, Susceptibility To Lung Cancer, Protection Against Adenocarcinoma Of Lung, Somatic Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer Lung Neoplasm Carcinoma Of Lung Lung Non-Small Cell Carcinoma Non-Small Cell Lung Cancer Nsclc Lung Neoplasms Malignant Neoplasm Of Lung Alveolar Cell Carcinoma Nonsmall Cell Lung Cancer, Somatic Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer, Susceptibility To Lung Cancer, Somatic Lung Cancer, Resistance To Cancer Of Lung Cancer Of Bronchus Cancer Of The Lung Lung Malignancies Lung Malignant Tumors Malignant Lung Tumor Malignant Tumor Of Lung Pulmonary Cancer Pulmonary Carcinoma Pulmonary Neoplasms Respiratory Carcinoma LNCR Adenocarcinoma Of Lung Neoplasm Of Lung Cancer Lung Carcinoma Non-Small Cell Lung Carcinoma, Non-Small-Cell Lung Lung Cancers Lung Carcinomas Cancer, Lung Cancer, Lung, Non-Small Cell Primary Malignant Neoplasm Of Lung Bronchioloalveolar Adenocarcinoma
Autoimmune Glomerulonephritis
T Cell Deficiency	T Cell Immunodeficiency T Lymphocyte Deficiency T Lymphocyte Immunodeficiency T-Lymphocyte Deficiency
Filarial Elephantiasis	Lymphatic Filariasis Elephantiasis Filariasis Bancroftian Elephantiasis Bancroftian Filarial Chyluria Elephantiasis Of Eyelid Bancroftian Filariasis Elephantitis Malayi Tropical Eosinphilia Wuchereria Bancrofti Infection Wuchereriasis Elephantiasis, Filarial Filarial Elephantiases Infection By Wuchereria Bancrofti Filarial Lymphangitis Tropical Elephantiasis Filarial Chylocele
Autoimmune Disease Of Skin And Connective Tissue
Dacryoadenitis	Dacryocystitis
Integumentary System Disease
Adult T-Cell Leukemia/Lymphoma	Adult T-Cell Leukemia Atll Adult T-Cell Leukaemia Adult T-Cell Leukaemia/Lymphoma Adult T-Cell Lymphoma T Cell Leukemia Lymphoma Adult Leukemia-Lymphoma, Adult T-Cell Leukemia, T-Cell Adult T-Cell Lymphoma/Leukemia
Autoimmune Disease Of Blood
B Cell Deficiency	Immunoglobulin Heavy Chain Deficiency B Cell Deficiencies Immunoglobulin Heavy Chain Deletion Humoral Immune Defect
Contact Dermatitis	Contact Dermatitis/Eczema Contact Eczema Dermatitis Venenata Dermatitis, Venenata Dermatitis Contact Dermatitis, Contact
Bone Inflammation Disease	Osteitis Bone Inflammatory Disease Inflammatory Disorder Of Bone
Anemia, Autoimmune Hemolytic	Autoimmune Hemolytic Anemia Idiopathic Autoimmune Hemolytic Anemia Immuno-Hemolytic Anemia Anemia, Hemolytic, Autoimmune Autoimmune Haemolytic Anaemia Autoimmune Hemolytic Anaemia Acquired Autoimmune Hemolytic Anemia Anemia Hemolytic Autoimmune Familial Auto-Immune Hemolytic Anemia Aha Aiha
Uveal Disease	Uveal Diseases
Demyelinating Disease	Demyelinating Diseases Demyelinating Disorder
T-Cell Acute Lymphoblastic Leukemia	T-Cell Leukemia Acute T Cell Leukemia Precursor T Lymphoblastic Leukemia Precursor T-Lymphoblastic Lymphoma/Leukemia T Acute Lymphoblastic Leukemia T-Cell Acute Lymphocytic Leukaemia T-Cell Lymphoblastic Leukemia/Lymphoma Leukemia T-Cell Leukemia, T-Cell Leukemia, Acute, Lymphoblastic, T-Cell Leukemia, T-Cell Acute Lymphoblastic Leukemia, Acute T-Cell Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Precursor T-Cell Lymphoblastic Lymphoma Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Hypersensitivity Reaction Type Iv Disease	Immunoproliferative Disorders Immunoproliferative Disease
Crohn'S Disease	Crohn Disease Pediatric Crohn'S Disease Regional Enteritis Crohn'S Disease Of Large Bowel Granulomatous Colitis Enteritis, Granulomatous Enteritis Crohn'S Disease Of Colon Colitis, Granulomatous Crohn'S Enteritis Enteritis, Regional Ileitis Adenoviral Enteritis Acute Gastroenteropathy Due To Norwalk Agent Viral Gastroenteritis Due To Norwalk Agent Winter Vomiting Epidemic Winter Vomiting Disease Small Round Structured Virus Enteritis Epidemic Vomiting Syndrome Epidemic Vomiting Epidemic Nausea Epidemic Viral Gastroenteritis Due To Norwalk Virus Noroviral Enteritis Crohn Disease Nos Crohns Cd - [Crohn'S Disease] Regional Enteritis Of Bowel Crohn'S Regional Enteritis Cobble-Stone Appearance Of Intestine Intestinal Ulcer And Erosion Due To Crohn Disease Granulomatous Enteritis
Early Congenital Syphilis
Allergic Contact Dermatitis	Dermatitis, Allergic Contact Contact Dermatitis, Allergic Dermatitis Allergic Contact Allergic Contact Eczema Acd - [Allergic Contact Dermatitis] Allergic Contact Dermatitis, Unspecified Cause Allergic Dermatitis Allergic Eczema Allergy Dermatitis Allergy Eczema Allergic Contact Eczema Due To Clothing Or Footwear Perfume Allergic Contact Dermatitis Allergic Contact Dermatitis Due To Cosmetics Allergic Contact Eczema Due To Cosmetics Or Fragrances Allergic Contact Eczema Due To Dental Materials Allergic Contact Eczema Due To Food Flavours Or Additives Allergic Contact Eczema Due To Hairdressing Products Allergic Contact Eczema Due To Metals Or Metal Salts Allergic Contact Eczema Due To Proteins Allergic Contact Eczema Due To Plastics Or Resin Systems Allergic Contact Eczema Due To Preservatives Or Biocides Allergic Contact Eczema Due To Rubber Chemicals Rubber Dermatitis Allergic Contact Eczema Due To Systemic Medicaments Allergic Contact Eczema Due To Topical Medicaments Allergic Contact Dermatitis Due To Drugs In Contact With Skin
Vitiligo-Associated Multiple Autoimmune Disease Susceptibility 1	Vitiligo VAMAS1 Slev1 Vtlg Systemic Lupus Erythematosus, Vitiligo-Related Vitiligo-Associated Multiple Autoimmune Disease 1 Systemic Lupus Erythematosus Vitiligo-Related
Autoimmune Disease Of Cardiovascular System
Autoimmune Disease Of Exocrine System
Rectal Disease	Rectal Diseases Rectal Disorders
Combined Immunodeficiency	Combined T Cell And B Cell Immunodeficiency Congenital Combined Immunodeficiency Syndrome With Combined Immunodeficiency Combined T And B Cell Immunodeficiency Combined Immunity Deficiency Combined Immunodeficiency Syndrome Combined T-Cell And B-Cell Immunodeficiency Lymphopenic Agammaglobulinaemia
Orchitis	Inflammation Of Testis Orchititis Mumps Orchitis
Bone Cancer	Malignant Bone Neoplasm Bone Carcinoma Bone Neoplasms Bone Neoplasm Bone Tumour Ca - Bone Cancer Malignant Bone Tumour Malignant Neoplasm Of Bone Malignant Osseous Tumor Neoplasm Of Bone Osseous Tumor Osteosarcoma Of Bone Osteogenic Neoplasm
Immune Deficiency Disease	Immunodeficiency Primary Immunodeficiency Primary Immunodeficiency Disease Immunologic Deficiency Syndromes Hypoimmunity Immune Deficiency Disorder Immunodeficiency Syndrome Immune Disorder Primary Immune Deficiency Disorder Immune System Diseases Human Immunodeficiency Virus Infection Hiv - [Human Immunodeficiency Virus Infection] Hiv Positive Nos Hiv Disease Acquired Immune Deficiency Syndrome-Related Complex Aids-Like Syndrome Aids-Related Complex Nos Arc - [Aids-Related Complex] Immunodeficiency Due To Human Immunodeficiency Virus Infection Unspecified Human Immunodeficiency Virus Disease Hiv Disease Nos Human Immunodeficiency Virus Positive Nos Hiv Nos Deficiency Of Complement Initial Pathway Deficiency Of Complement Terminal Pathway Cfdd - [Complement Factor D Deficiency] Immunodeficiency With Nk-Cell - [Natural-Killer Cell] Deficiency Nonfamilial Hypogammaglobulinaemia Common Variable Immune Deficiency Nonfamilial Agammaglobulinaemia Common Variable Agammaglobulinaemia Agammaglobulinaemia Nos Agammaglobulinaemia Antibody Deficiency Syndrome Hypogammaglobulinaemia Antibody Deficiency Syndrome Acquired Agammaglobulinaemia Nos Hypogammaglobulinaemia Nos Hyper Igm
Thymus Gland Disease	Disease Of Thymus Gland
Permanent Neonatal Diabetes Mellitus	Pndm Permanent Diabetes Mellitus Of Infancy Pdmi Neonatal Diabetes Mellitus, Permanent
Hepatocellular Carcinoma	Liver Cancer Primary Liver Cancer HCC Hepatoma Malignant Neoplasm Of Liver Liver Neoplasms Cancer, Hepatocellular Liver Cell Carcinoma Lcc Hepatoblastoma, Somatic Hepatic Cancer Primary Malignant Neoplasm Of Liver Rare Tumor Of Liver And Intrahepatic Biliary Tract Hepatocellular Carcinoma, Somatic Hepatocellular Carcinoma, Childhood Type, Somatic Hepatocellular Cancer, Somatic Ca Liver - Primary Hepatic Neoplasm Malignant Hepato-Biliary Neoplasm Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary Malignant Neoplasm Of Liver, Primary Malignant Tumor Of Liver Neoplasm Of Liver Non-Resectable Primary Hepatic Malignant Neoplasm Resectable Malignant Neoplasm Of Liver Resectable Malignant Neoplasm Of The Liver Primary Liver Carcinoma Primary Malignant Liver Neoplasm Primary Cancer Of Liver Primary Tumor Of The Liver Rare Tumor Of Liver And Ibt Hepatocellular Cancer Neoplasm Of The Liver Carcinoma, Hepatocellular Hepatomas Liver Neoplasm Liver Carcinoma Liver And Intrahepatic Biliary Tract Carcinoma Malignant Hepatobiliary Neoplasm Adult Primary Hepatocellular Carcinoma Hepatoblastoma Carcinoma Of Liver Malignant Liver Tumour Malignant Hepatic Tumour
Leukocyte Disease	Leukocyte Disorders
Thymus Cancer	Thymic Neoplasm Thymic Tumor Thymus Neoplasm Thymus Neoplasms Malignant Neoplasm Of Thymus Neoplasm Of Thymus Thymic Neoplasms Thymoma, Familial Thymic Carcinoma Thymoma, Type C Cancer Of Thymus Malignant Tumour Of Thymus Primary Malignant Neoplasm Of Thymus Thymic Glandular Cancer Thymus Gland Cancer
Primary Bacterial Infectious Disease
Parasitic Protozoa Infectious Disease	Protozoan Infections Mastigophora Infectious Disease Sarcomastigophora Infectious Disease
Immune System Disease	Abnormality Of The Immune System Immune System And Disorders Immune System Diseases
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Autoimmune Lymphoproliferative Syndrome	ALPS Canale-Smith Syndrome Autoimmune Lymphoproliferative Syndrome, Type Ia Autoimmune Lymphoproliferative Syndrome, Type Ib Autoimmune Lymphoproliferative Syndrome Type 1, Autosomal Dominant Css Autoimmune Lymphoproliferative Syndrome, Type 1b Autoimmune Lymphoproliferative Syndrome, Type 1a Autoimmune Lymphoproliferative Syndrome, Type I, Autosomal Dominant Fas Deficiency Autoimmune Lymphoproliferative Syndrome 1a ALPS1A Autoimmune Lymphoproliferative Syndrome Type Ia Autoimmune Lymphoproliferative Syndrome 1b ALPS1B Autoimmune Lymphoproliferative Syndrome Type Ib
Celiac Disease 1	Celiac Disease Coeliac Disease Celiac Sprue Celiac Disease, Susceptibility To Gluten-Sensitive Enteropathy Nontropical Sprue Sprue CELIAC1 Celiac Disease, Susceptibility To, 1 Celiac Sprue 1 Celiac Sprue, Susceptibility To, 1 Gluten-Sensitive Enteropathy 1 Gluten-Sensitive Enteropathy, Susceptibility To, 1 Idiopathic Steatorrhea Cœliac Disease Gluten Intolerance Gluten-Induced Enteropathy Gluten Enteropathy Celiac Disease, Susceptibility To, Type 1 Childhood Celiac Disease Coeliac Rickets Gee Disease Gee-Herter Disease Heubner-Herter Disease Idiopathic Steatorrhoea Thaysen'S Disease Herter Gee Syndrome
Chronic Mucocutaneous Candidiasis	Candidiasis, Chronic Mucocutaneous Cmc Candidiasis Chronic Mucocutaneous
Bone Squamous Cell Carcinoma
Leprosy 3	Leprosy Leprosy, Susceptibility To, 3 Hansen'S Disease Leprosy, Susceptibility To Hansen Disease Infection Due To Mycobacterium Leprae LPRS3 Leprosy, Type 3 Anaesthesia Leprosy Anaesthetic Leprosy Maculoanaesthetic Leprosy Macular Leprosy Leprosy Unspecified
Sezary'S Disease	Sezary Syndrome Sézary Syndrome Sezary'S Lymphoma Sezary Disease Sezary Erythroderma Sezary Lymphoma
Potocki-Shaffer Syndrome	Proximal 11p Deletion Syndrome Chromosome 11p11.2 Deletion Syndrome Pss 11p11.2 Deletion P11pds Defect11 Syndrome Deletion Of Chromosome 11p11.2 POSHS
Breast Cancer	Breast Carcinoma Male Breast Cancer Breast Cancer, Familial Malignant Neoplasm Of Breast Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation
Behcet Syndrome	Behcet Disease Behcet'S Syndrome Behcet'S Disease Behçet Disease Bd Adamantiades-Behcet Disease Triple Symptom Complex Behçet'S Disease Behet'S Syndrome Bd Syndrome Behçet Syndrome Behçet'S Syndrome Behcet Triple Symptom Complex Malignant Aphthosis Old Silk Route Disease Adamantiades-Behçet Disease
Esophageal Cancer	Esophageal Carcinoma Carcinoma Of Esophagus Esophageal Squamous Cell Carcinoma, Somatic Esophageal Carcinoma, Somatic Esophagus Cancer Gastric Cardia Adenocarcinoma Esophageal Neoplasms Esophageal Cancer, Somatic Cancer Of Esophagus Cancer Of Oesophagus Carcinoma Of Oesophagus Ca Lower Third Oesophagus Ca Middle Third Oesophagus Malignant Neoplasm Of Distal Third Of Esophagus Malignant Neoplasm Of Lower Third Of Oesophagus Malignant Neoplasm Of Middle Third Of Oesophagus Malignant Neoplasm Of Proximal Third Of Esophagus Malignant Neoplasm Of Upper Third Esophagus Malignant Tumor Of Abdominal Esophagus Malignant Tumor Of Distal Third Of Esophagus Malignant Tumor Of Proximal Third Of Esophagus Malignant Tumor Of The Middle Third Of The Esophagus ESCR Aerodigestive Tract Cancer Escc Esophageal Squamous Cell Carcinoma Cancer, Esophageal Malignant Neoplasm Of Esophagus Squamous Cell Carcinoma Of Esophagus Malignant Neoplasm Of Middle Third Of Esophagus
Dermatitis, Atopic	Atopic Dermatitis Atopic Eczema Dermatitis, Atopic, Susceptibility To, 1 Atod Eczema, Atopic Dermatitis, Atopic 1 Allergic Dermatitis Atopic Neurodermatitis Besnier'S Prurigo Dermatitis, Atopic, 1 Dermatitis Atopic Eczema Besnier Prurigo
Renal Cell Carcinoma, Nonpapillary	Renal Cell Carcinoma RCC Nonpapillary Renal Cell Carcinoma Clear Cell Renal Cell Carcinoma Hypernephroma Adenocarcinoma Of Kidney Renal Carcinoma, Chromophobe, Somatic Clear Cell Carcinoma Of Kidney Clear-Cell Metastatic Renal Cell Carcinoma Clear Cell Renal Carcinoma Renal Cell Carcinoma, Somatic Conventional Renal Cell Carcinoma Conventional Renal Cell Carcinoma Renal Clear Cell Carcinoma Ccrcc Hereditary Clear Cell Renal Cell Carcinoma Carcinoma, Renal Cell Renal Cell Carcinoma, Clear Cell, Somatic Renal Cell Carcinoma, Clear Cell Clear Cell Kidney Carcinoma Clear Cell Rcc Cystic-Multilocular Variant Clear Cell Renal Cell Adenocarcinoma Hereditary Clear Cell Renal Cell Adenocarcinoma Common Renal Cell Carcinoma Crcc Renal Cell Carcinoma Non-Papillary Carcinoma Renal Cell Renal Cell Cancer Carcinoma, Renal Cell, Nonpapillary
Cholangitis, Primary Sclerosing	Primary Sclerosing Cholangitis PSC Sclerosing Cholangitis Cholangitis, Sclerosing Cholangitis Primary Sclerosing Psc - [Primary Sclerosing Cholangitis]
Skin Disease	Skin Diseases Genodermatosis Abnormality Of The Skin Skin Diseases, Genetic Skin And Subcutaneous Tissue Disease Dermatologic Disorders
Autism	Autistic Disorder Autism Susceptibility 1 Childhood Autism Autistic Disorder Of Childhood Onset Infantile Autism Kanner'S Syndrome Autistic
Severe Combined Immunodeficiency	Scid Severe Combined Immunodeficiency Disease Combined T And B Cell Inborn Immunodeficiency Immunodeficiency, Severe Combined Scid - [Severe Combined Immunodeficiencies]
Colonic Benign Neoplasm	Colon Neoplasm Colonic Mass Colonic Tumor Neoplasm Of Colon Neoplasm Of The Colon Colonic Neoplasms Colon Cancer Colon Carcinoma Nos Colonic Cancer Metastatic Colon Cancer Nos
Connective Tissue Disease	Connective Tissue Diseases Connective Tissue Disorder Abnormality Of Connective Tissue Disorder Of Connective Tissue Connective Tissue Disorders
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder
Eye Disease	Eye Diseases Abnormality Of The Eye Toxoplasma Oculopathy
Peripheral Nervous System Disease	Peripheral Neuropathy Peripheral Nerve Disease Peripheral Nerve Disorders Neuropathy, Peripheral Peripheral Neuropathy Due To Vitamin Pyridoxine Hyperalimentation
Leukemia, Acute Myeloid	Acute Myeloid Leukemia Leukemia, Acute Myelogenous Acute Myelogenous Leukemia AML Leukemia, Acute Myeloid, Susceptibility To Acute Myeloblastic Leukemia Leukemia, Acute Myeloid, Reduced Survival In, Somatic Acute Myeloid Leukaemia Leukemia, Myelocytic, Acute Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome Secondary Aml Acute Myelocytic Leukemia Acute Myeloid Leukemia, Somatic Leukemia, Acute Myeloid, Somatic Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic Acute Myeloblastic Leukaemia Acute Myelogenous Leukaemia Aml - Acute Myeloid Leukemia Acute Myeloid Leukemia With Cebpa Somatic Mutations Aml With Cebpa Somatic Mutations Inherited Acute Myeloid Leukemia Familial Aml Inherited Aml Pure Familial Aml Pure Familial Acute Myeloid Leukemia Secondary Acute Myeloid Leukemia Therapy-Related Aml And Myelodysplastic Syndrome Acute Myeloid Leukemia, Secondary Acute Non-Lymphoblastic Leukemia Acute Non-Lymphocytic Leukemia Acute Biphenotypic Leukemia Acute Undifferentiated Leukemia Acute Myeloblastic Leukaemia With Multilineage Dysplasia Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission Acute Myeloid Leukaemia With Myelodysplasia-Related Features

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

Bioactive Molecules (2)

製品番号	製品名	製品効果	純度	Rare Diseases
HY-13624A	Epirubicin hydrochloride	Inhibitor	99.62%	Yes
HY-13624	Epirubicin	Inhibitor	99.61%	Yes

Clinical Phase

Bioactive Molecules (1)

製品番号	製品名	製品効果	純度	Phase
HY-159692A	AZD8701 sodium	Inhibitor	96.61%	Phase 1

Pre-clinical Phase

Bioactive Molecules (7)

製品番号	製品名	製品効果	純度	Rare Diseases
HY-P1684	Peptide P60	Inhibitor	98.39%	Unkown
HY-124131	DS-437	Inhibitor	99.22%	Unkown
HY-162943	P60-L3-VHL	Degrader	99.84%	Unkown
HY-P1453A	CMD178 TFA	Inhibitor	99.71%	Unkown
HY-159692	AZD8701	Inhibitor	96.61%	Unkown
HY-162946	Alkyne-P60	Inhibitor	99.96%	Unkown
HY-P1453	CMD178	Inhibitor	/	Unkown

Orthologs Information

生物種	Symbol	由来	ID
Felis catus	FOXP3	VGNC	VGNC:67815
Bos taurus	FOXP3	VGNC	VGNC:29102
Mus musculus	FOXP3	MGD	MGI:1891436
Macaca mulatta	FOXP3	VGNC	VGNC:72926
Canis familiaris	FOXP3	VGNC	VGNC:40967
Rattus norvegicus	FOXP3	RGD	RGD:1562112
Others	FOXP3	NCBI