Lambertellin
Lambertellin is an effective antibiotic that can be used as a bactericide and as a fungicide. Lambertellin exerts its anti-inflammatory effect in LPS (HY-D1056)-stimulated RAW 264.7 macrophage cells by modulating the activation of the MAPK and NF-κB signaling pathways.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 28980-51-0
- 分子式: C14H8O5
- 分子量:256.21
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Antibiotic アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
体外実験
In lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells, Lambertellin exhibits promising inhibitory activity against nitric oxide (NO) production with an IC50 value of 3.19 µM, and it significantly inhibits the expression of inducible NO synthase (iNOS) and cyclooxygenase 2 (COX-2). Lambertellin also decreases the expression of pro-inflammatory cytokines IL-6 and IL-1β[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 28980-51-0
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分子量 256.21
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分子式 C14H8O5
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SMILES
O=C1OC(C(C2=C3C=CC=C2O)=O)=C(C=C1C)C3=O
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Structure Classification
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Initial Source
Lambertella sp.
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Lambertellin 関連分類
HY-124508 関連分類
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