Norcyclizine
Based on 1 Customer Validation
Norcyclizine is a piperazine compound that can be used for the synthesis of antimicrobial agents. 1-Benzhydrylpiperazine derivatives have been found to enhance the antibacterial activity of β-lactam antibiotics (Oxacillin, HY-B0925A) against Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA). This enhancement is likely achieved by inhibiting the allosteric site of PBP2a. Additionally, 1-Benzhydrylpiperazine can also serve as a pharmacological scaffold for the synthesis of anticancer agents.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 841-77-0
- 分子式: C17H20N2
- 分子量:252.35
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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生物活性
化学情報
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CAS 番号 841-77-0
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性状 Solid
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分子量 252.35
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分子式 C17H20N2
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Color White to off-white
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SMILES
C1(C(N2CCNCC2)C3=CC=CC=C3)=CC=CC=C1
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別名
1-(Diphenylmethyl)piperazine; 1-Benzhydrylpiperazine
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (950 KB)
- English - EN (950 KB)
- Français - FR (950 KB)
- Deutsch - DE (950 KB)
- Norwegian - NO (950 KB)
- Español - ES (950 KB)
- Swedish - SV (950 KB)
- Italian - IT (950 KB)
- Korean - KR (950 KB)
- Portuguese - PT (950 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Witek K, et al. Chalcogen-Varied Imidazolone Derivatives as Antibiotic Resistance Breakers in Staphylococcus aureus Strains. Antibiotics (Basel). 2023 Nov 11;12(11):1618. [Content Brief]
[2]. Ananda Kumar CS et al. Synthesis and in vitro antiproliferative activity of novel 1-benzhydrylpiperazine derivatives against human cancer cell lines. Eur J Med Chem. 2009 Mar;44(3):1223-9. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Norcyclizine 関連分類
HY-W013376 関連分類
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