Ponometrep
Based on 1 Customer Validation
Ponometrep (BHV-2100) is a transient receptor potential melastatin 3 (TRPM3) antagonist with IC50 values of 1-10 nM. Ponometrep shows analgesic activity and can be used for the research of neurological diseases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.28%
- CAS 番号: 2776175-74-5
- 分子式: C18H19N3O5S
- 分子量:389.43
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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Membrane Transporter/Ion Channel Compound Library
HY-L011
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Neuronal Signaling Compound Library
HY-L013
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Clinical Compound Library
HY-L026
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Drug Repurposing Compound Library
HY-L035
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Mechanoreceptors Compound Library
HY-L095
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Pain-Related Compound Library
HY-L139
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Membrane Protein-targeted Compound Library
HY-L149
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Membrane Receptor-targeted Compound Library
HY-L150
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Ion Channel Compound Library
HY-L166
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Drug Repurposing Compound Library Plus
HY-L035P
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Clinical Compound Library Plus
HY-L026P
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Bioactive Compound Library
HY-L001
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High-Throughput Bioactive Compound Library
HY-L205
生物活性
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TRPM3 1-10 nM (IC50) |
Ponometrep inhibits human, mouse, and rat TRPM3 with IC50 values between 1-10 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
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CAS 番号 2776175-74-5
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性状 Solid
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分子量 389.43
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分子式 C18H19N3O5S
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Color White to light yellow
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SMILES
CC1=NC=C(S1)COC2=CC=C3OC(C)=C(C3=C2)C(N[C@H](C(N)=O)CO)=O
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別名
BHV-2100
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 50 mg/mL (128.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5679 mL | 12.8393 mL | 25.6786 mL | 64.1964 mL |
| 5 mM | 0.5136 mL | 2.5679 mL | 5.1357 mL | 12.8393 mL | |
| 10 mM | 0.2568 mL | 1.2839 mL | 2.5679 mL | 6.4196 mL | |
| 15 mM | 0.1712 mL | 0.8560 mL | 1.7119 mL | 4.2798 mL | |
| 20 mM | 0.1284 mL | 0.6420 mL | 1.2839 mL | 3.2098 mL | |
| 25 mM | 0.1027 mL | 0.5136 mL | 1.0271 mL | 2.5679 mL | |
| 30 mM | 0.0856 mL | 0.4280 mL | 0.8560 mL | 2.1399 mL | |
| 40 mM | 0.0642 mL | 0.3210 mL | 0.6420 mL | 1.6049 mL | |
| 50 mM | 0.0514 mL | 0.2568 mL | 0.5136 mL | 1.2839 mL | |
| 60 mM | 0.0428 mL | 0.2140 mL | 0.4280 mL | 1.0699 mL | |
| 80 mM | 0.0321 mL | 0.1605 mL | 0.3210 mL | 0.8025 mL | |
| 100 mM | 0.0257 mL | 0.1284 mL | 0.2568 mL | 0.6420 mL |
Ponometrep 関連分類
HY-182466 関連分類
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