PRMT5-IN-2
Based on 1 Customer Validation
PRMT5-IN-2 is a rotein arginine methyltransferase 5 (PRMT5) inhibitor extracted from patent WO2018130840A1, compound 3.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.68%
- CAS 番号: 1989620-04-3
- 分子式: C17H16ClFN4O4
- 分子量:394.78
-
保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
-
溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
-
Epigenetics Compound Library
HY-L005
-
Histone Modification Research Compound Library
HY-L024
-
Anti-Cancer Compound Library
HY-L025
-
Reprogramming Compound Library
HY-L039
-
Anti-Blood Cancer Compound Library
HY-L079
-
Heterocyclic Compound Library
HY-L138
-
Anti-Hematopathy Compound Library
HY-L171
-
Bioactive Compound Library Max
HY-L181
-
MCE Bioactive Compound Library
HY-L001V
-
Bioactive Compound Library
HY-L001
-
Methylation Compound Library
HY-L203
-
High-Throughput Bioactive Compound Library
HY-L205
-
Posttranslational Modification Library
HY-L226
Histone Methyltransferase アイソフォーム固有の製品をすべて表示
More
生物活性
PRMT5[1]
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Z-138 | IC50 |
1.4 nM
Compound: PF-0685580; 4
|
Antiproliferative activity against human Z138 cells
Antiproliferative activity against human Z138 cells
|
[PMID: 30956011] |
化学情報
-
CAS 番号 1989620-04-3
-
性状 Solid
-
分子量 394.78
-
分子式 C17H16ClFN4O4
-
Color Off-white to light yellow
-
SMILES
O[C@H]1[C@@H](O[C@@]([C@@H](C2=CC(F)=C(Cl)C=C2)O)([H])[C@H]1O)N3C4=NC=NC(N)=C4C=C3
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 125 mg/mL (316.63 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (270 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5331 mL | 12.6653 mL | 25.3306 mL | 63.3264 mL |
| 5 mM | 0.5066 mL | 2.5331 mL | 5.0661 mL | 12.6653 mL | |
| 10 mM | 0.2533 mL | 1.2665 mL | 2.5331 mL | 6.3326 mL | |
| 15 mM | 0.1689 mL | 0.8444 mL | 1.6887 mL | 4.2218 mL | |
| 20 mM | 0.1267 mL | 0.6333 mL | 1.2665 mL | 3.1663 mL | |
| 25 mM | 0.1013 mL | 0.5066 mL | 1.0132 mL | 2.5331 mL | |
| 30 mM | 0.0844 mL | 0.4222 mL | 0.8444 mL | 2.1109 mL | |
| 40 mM | 0.0633 mL | 0.3166 mL | 0.6333 mL | 1.5832 mL | |
| 50 mM | 0.0507 mL | 0.2533 mL | 0.5066 mL | 1.2665 mL | |
| 60 mM | 0.0422 mL | 0.2111 mL | 0.4222 mL | 1.0554 mL | |
| 80 mM | 0.0317 mL | 0.1583 mL | 0.3166 mL | 0.7916 mL | |
| 100 mM | 0.0253 mL | 0.1267 mL | 0.2533 mL | 0.6333 mL |
PRMT5-IN-2 関連分類
HY-112165 関連分類
Powered by Bioz