Solavetivone
Solavetivone is a Sesquiterpenoid phytoalexin and Antifungal agent. Solavetivone is isolated from stress-challenged potato plants. Solavetivone is hydroxylated by sesquiterpenoid phytoalexin hydroxylase (SPH/CYP76A2L). Solavetivone helps solanaceous plants defend against pathogens, damages plant cells after pathogen threat, and inhibits mycelial growth of Rhizoctonia solani. Solavetivone is applicable to studies related to Rhizoctonia solani infection.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 54878-25-0
- 分子式: C15H22O
- 分子量:218.33
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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CYP76A2L |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| OVCAR-3 | IC50 |
0.1 mM
Compound: 1, Solavetivone
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Cytotoxicity against human OVCAR-3 cells
Cytotoxicity against human OVCAR-3 cells
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[PMID: 11575964] |
Solavetivone (3.2-16.1 μg/mL; 48 h) inhibits in vitro mycelial growth of Rhizoctonia solani in a concentration-dependent manner, with 27.6% inhibition observed at 16.1 μg/mL after 48 h incubation[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 54878-25-0
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分子量 218.33
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分子式 C15H22O
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SMILES
C[C@H]1[C@@]2(C(C)=CC(C1)=O)C[C@@H](CC2)C(C)=C
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Camagna M, et al. Detoxification of the solanaceous phytoalexins rishitin, lubimin, oxylubimin and solavetivone via a cytochrome P450 oxygenase. Plant Signal Behav. 2020;15(2):1707348. [Content Brief]
[3]. Yao MK, et al. Effect of mycorrhization on the accumulation of rishitin and solavetivone in potato plantlets challenged with Rhizoctonia solani. Mycorrhiza. 2003;13(6):333-336. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
- Solavetivone
- 54878-25-0
- Fungal
- Cytochrome P450
- sesquiterpenoid phytoalexins hydroxylase
- Glomus etunicatum
- Hyoscyamus muticus
- calcium-alginate immobilized Hyoscyamus muticus cells
- Solanum plants
- Rhizoctonia solani
- Nicotiana benthamiana
- SPH/CYP76A2L
- Solanum tuberosum cv. Goldrush
- potato roots
- Inhibitor
- inhibitor
- inhibit