XAP044
Based on 1 Customer Validation
XAP044 is a potent and selective antagonist of mGlu7. The metabotropic glutamate receptor subtype 7 (mGlu7) is an important presynaptic regulator of neurotransmission in the mammalian CNS. XAP044 demonstrates good brain exposure and wide spectrum anti-stress and antidepressant- and anxiolytic-like efficacy in rodent behavioral paradigms.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.99%
- CAS 番号: 196928-50-4
- 分子式: C15H9IO4
- 分子量:380.13
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保管条件:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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AZ 12216052mGluR8 PAM -
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MPEP Hydrochloride (Standard)mGlu5 Receptor Antagonist
生物活性
製品説明
化学情報
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CAS 番号 196928-50-4
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性状 Solid
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分子量 380.13
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分子式 C15H9IO4
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Color White to off-white
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SMILES
O=C1C2=CC=C(O)C=C2OC=C1OC3=CC=C(I)C=C3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
溶剤 & 溶解度
体外:
DMSO : ≥ 50 mg/mL (131.53 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6307 mL | 13.1534 mL | 26.3068 mL | 65.7670 mL |
| 5 mM | 0.5261 mL | 2.6307 mL | 5.2614 mL | 13.1534 mL | |
| 10 mM | 0.2631 mL | 1.3153 mL | 2.6307 mL | 6.5767 mL | |
| 15 mM | 0.1754 mL | 0.8769 mL | 1.7538 mL | 4.3845 mL | |
| 20 mM | 0.1315 mL | 0.6577 mL | 1.3153 mL | 3.2883 mL | |
| 25 mM | 0.1052 mL | 0.5261 mL | 1.0523 mL | 2.6307 mL | |
| 30 mM | 0.0877 mL | 0.4384 mL | 0.8769 mL | 2.1922 mL | |
| 40 mM | 0.0658 mL | 0.3288 mL | 0.6577 mL | 1.6442 mL | |
| 50 mM | 0.0526 mL | 0.2631 mL | 0.5261 mL | 1.3153 mL | |
| 60 mM | 0.0438 mL | 0.2192 mL | 0.4384 mL | 1.0961 mL | |
| 80 mM | 0.0329 mL | 0.1644 mL | 0.3288 mL | 0.8221 mL | |
| 100 mM | 0.0263 mL | 0.1315 mL | 0.2631 mL | 0.6577 mL |
XAP044 関連分類
HY-110146 関連分類
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