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Cat. No.: HY-161162

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aTAG 2139

(Synonyms: CFT-2139)

aTAG 2139 (CFT-2139) is an aTAG-based MTH1 fusion protein degrader with a DC₅₀ value of 1.1 nM. aTAG 2139 has a Ki value of 2.1 nM for MTH1.

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CAS No.: 2387510-81-6
화학식: C₄₂H₃₈N₈O₈
분자량:782.80

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

aTAG 2139 Chemical Structure

CAS No.: 2387510-81-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

aTAG 2139 (CFT-2139) is an aTAG-based MTH1 fusion protein degrader with a DC₅₀ value of 1.1 nM. aTAG 2139 has a Ki value of 2.1 nM for MTH1^[1].

All DNA/RNA Synthesis Isoforms :

Chemical Information

CAS No. 2387510-81-6
분자량 782.80
화학식 C₄₂H₃₈N₈O₈
SMILES

O=C(C1=CC=C(C2=CC=C3N=CC(C(NC)=O)=C(C3=C2)NC4=CC=CC=C4)C=N1)NCCCCNC(COC5=CC=CC(C(N6C7C(NC(CC7)=O)=O)=O)=C5C6=O)=O
Synonyms

CFT-2139
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Veits G K, et al. Development of an AchillesTAG degradation system and its application to control CAR-T activity[J]. Current Research in Chemical Biology, 2021, 1: 100010.

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

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Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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aTAG 2139

All DNA/RNA Synthesis Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

aTAG 2139 Related Classifications

HY-161162 Related Classifications