BRD9185
BRD9185 is a Dihydroorotate dehydrogenase (DHODH) inhibitor, with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro and is curative after just three doses in a P. berghei mouse model.
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- CAS No.: 2057420-29-6
- 화학식: C23H21F6N3O2
- 분자량:485.42
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
EC50: 16 nM (DHODH in vitro)[1].
Chemical Information
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CAS No. 2057420-29-6
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분자량 485.42
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화학식 C23H21F6N3O2
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SMILES
O=C(N1[C@@H]([C@H]([C@H]1C#N)C2=CC=C(C3=CC=C(C(C(F)(F)F)=C3)C(F)(F)F)C=C2)CO)NCCC
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)