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Cat. No.: HY-184911

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CDK6 ligand-3

CDK6 ligand-3 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs) that targets CDK6. CDK6 ligand-3 can be used to synthesize the PROTAC JHK-02-108-2 (HY-184910).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₂₆H₂₆F₄N₆O₃
분자량:546.52

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

CDK6 ligand-3 Chemical Structure

사이즈

가격

재고

수량

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

CDK6

All CDK Isoforms :

In Vitro

CDK6 ligand-3 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs) that targets CDK6. CDK6 ligand-3 can be used to synthesize the PROTAC JHK-02-108-2 (HY-184910)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

분자량 546.52
화학식 C₂₆H₂₆F₄N₆O₃
SMILES

FC(F)(F)C(C=C(NC(NC1=C(F)C=C(OC2=CC(C(NC)=O)=NC=C2)C=C1)=O)C=C3)=C3CN4CCNCC4
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Kim JH, et al. A Type II CDK6 Degrader Enables Cellular Targeting beyond the Limits of Type II Inhibition. Journal of the American Chemical Society. 2026 Jul 08;148(26):27951-27964. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

상품명:
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CDK6 ligand-3

All CDK Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

CDK6 ligand-3 Related Classifications

HY-184911 Related Classifications