Chlortetracycline
Based on 7 publication(s) in Google Scholar
Chlortetracycline (7-Chlorotetracycline) is an orally active, effective and selectively methanogenic bacteria inhibitor with bactericidal effects. Chlortetracycline is also a antibiotic that acts by inhibiting bacterial protein synthesis. Additionally, Chlortetracycline is a specific and potent calcium ionophore antibiotic, inhibiting binding of aminoacyl-tRNA to ribosomes.
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- CAS No.: 57-62-5
- 화학식: C22H23ClN2O8
- 분자량:478.88
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보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) Chlortetracycline
More- Food Chem X. 2026 Feb 8:34:103646. [Abstract]
- Antibiotics (Basel). 2026 Jan 6;15(1):62. [Abstract]
- Sci Rep. 2022 Aug 25;12(1):14502. [Abstract]
- Biology (Basel). 2025 Jun 24;14(7):755. [Abstract]
- Saudi Pharm J. 2021 Jun;29(6):566-575. [Abstract]
- BMC Vet Res. 2025 Jul 23;21(1):485. [Abstract]
- Chemosphere. 2019 Jun:225:378-387. [Abstract]
All Antibiotic Isoforms
MoreAll Parasite Isoforms
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Biological Activity
제품 설명
IC50 & Target
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Tetracycline |
In Vitro
Chlortetracycline (10, 50, 100, 200 mg/L, 18 days) inhibits methane (a main component of biogas) production and is degradated and metabolized by anaerobic digestion (AD) at high concentrations and incubation temperatures[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:SPF level Kunming mice (KM)[4]
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Dosage:50 mg/kg
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Administration:p.o., administration for 42 consecutive days
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Result:Significantly increased the IgM antibody levels, decreased the IgA antibody levels and not influence IgG antibody levels in serum of mice.
Chemical Information
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CAS No. 57-62-5
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Appearance Solid
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분자량 478.88
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화학식 C22H23ClN2O8
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Color Light yellow to yellow
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SMILES
O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])[C@](C)(O)C4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4Cl)N
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Synonyms
7-Chlorotetracycline
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (7)
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Journal Impact Factor
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Most Recent
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Food Chem X
Machine learning prioritization of antibiotic residues in aquatic foods reveals exposure-driven genotoxic risk mediated by BCL2. [Abstract]2026 Feb 8:34:103646. PMID: 41756597 -
Antibiotics (Basel)
In Vitro and In Vivo Evaluation of Nitroxoline as an Effective Antimicrobial Alternative to Poultry Production. [Abstract]2026 Jan 6;15(1):62. PMID: 41594099 -
Sci Rep
Qualitative immunoassay for the determination of tetracycline antibiotic residues in milk samples followed by a quantitative improved HPLC-DAD method. [Abstract]2022 Aug 25;12(1):14502. PMID: 36008564 -
Biology (Basel)
Polysaccharide Supplements from Millettia speciosa Champ. ex Benth Enhance Growth and Meat Quality in Wenchang Chickens. [Abstract]2025 Jun 24;14(7):755. PMID: 40723316 -
Saudi Pharm J
Determination of tetracycline, oxytetracycline and chlortetracycline residues in seafood products of Saudi Arabia using high performance liquid chromatography-Photo diode array detection. [Abstract]2021 Jun;29(6):566-575. PMID: 34194263 -
BMC Vet Res
Dietary supplementation of polysaccharides from Millettia speciosa Champ. ex Benth on growth performance, immune function, antioxidant abilities and intestinal health of Wenchang chickens. [Abstract]2025 Jul 23;21(1):485. PMID: 40702452 -
Chemosphere
Mass-balance-model-based evaluation of sewage treatment plant contribution to residual pharmaceuticals in environmental waters. [Abstract]2019 Jun:225:378-387. PMID: 30884299
순도&문서
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Data Sheet (278 KB)
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SDS (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Elmund GK, et al. Role of excreted chlortetracycline in modifying the decomposition process in feedlot waste. Bull Environ Contam Toxicol. 1971 Mar-Apr;6(2):129-32. [Content Brief]
[2]. Saling PM, et al. Mouse gamete interactions during fertilization in vitro. Chlortetracycline as a fluorescent probe for the mouse sperm acrosome reaction. J Cell Biol. 1979 Dec;83(3):544-55. [Content Brief]
[4]. Liu D, et al. Synthesis and evaluation of bisulfate/mesylate-conjugated chlortetracycline with high solubility and bioavailability[J]. Acta Pharm. 2020 Dec 1;70(4):483-498. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Chlortetracycline Related Classifications
HY-B1327A Related Classifications
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