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Cat. No.: HY-158051

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CIDD-0072424

CIDD-0072424 selectively inhibits Protein Kinase C-epsilon (PKCε) (K_i=54 nM). CIDD-0072424 reduces ethanol consumption and preference in a dose-dependent manner.

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CAS No.: 1620195-03-0
화학식: C₂₄H₂₉ClN₄O₂
분자량:440.97

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

CIDD-0072424 Chemical Structure

CAS No.: 1620195-03-0

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

CIDD-0072424 selectively inhibits Protein Kinase C-epsilon (PKCε) (K_i=54 nM). CIDD-0072424 reduces ethanol consumption and preference in a dose-dependent manner^[1].

IC₅₀ & Target

^[1]

PKCε

54 nM (Ki)

All PKC Isoforms :

Chemical Information

CAS No. 1620195-03-0
분자량 440.97
화학식 C₂₄H₂₉ClN₄O₂
SMILES

N[C@@H]([C@]1([H])CC[C@@](CC1)([H])C(NC2=CC=NC=C2)=O)CNC(C3(CC3)C4=CC=C(C=C4)Cl)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. De Kraker H, et al. Asymmetric Synthesis of CIDD-0072424 via an Enantioselective Nitro-Mannich Reaction: A Central Nervous System Penetrant, Selective Small Molecule Inhibitor of Protein Kinase C Epsilon. J Org Chem. 2024 Apr 5;89(7):5134-5141. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

CIDD-0072424

All PKC Isoforms

Biological Activity

제품 설명

IC50 & Target

Chemical Information

순도&문서

References

Calculators

Help & FAQs

CIDD-0072424 Related Classifications

HY-158051 Related Classifications

Bioz

Keywords

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