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Cat. No.: HY-181976

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dHTC3

dHTC3 is a selective BRD4 molecular glue degrader. dHTC3 specifically recruits the first bromodomain of BRD4 to the E3 ubiquitin ligase complex (SCF^FBXO3), thereby triggering the ubiquitination and degradation of BRD4.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₃₁H₄₂N₆O₄S₂
분자량:626.83

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

dHTC3 Chemical Structure

사이즈

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

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Chemical Information

분자량 626.83
화학식 C₃₁H₄₂N₆O₄S₂
SMILES

O=C(OC(C)(C)C)C[C@H]1C2=NN=C(C)N2C3=C(C(C)=C(C)S3)C(C4=CC=C(NS(=O)(NCC5C(CC)(CC)C5)=O)C=C4)=N1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Shaum JB, et al. High-throughput ligand diversification to discover chemical inducers of proximity. Nat Chem Biol. 2026 Feb 16.
[Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
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Chemical Information
순도&문서
References

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dHTC3

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Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

dHTC3 Related Classifications

HY-181976 Related Classifications