DPQZ
DPQZ is an anti-tubulin agent that inhibits cell separation and induces cell cycle arrest at the G2/M phase. In addition, DPQZ induces caspase-dependent apoptosis of HSC-3 cells by inhibiting Ras/Raf and activating MAP kinase. DPQZ can be used in the study of oral cancer.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 1431362-93-4
- 화학식: C20H17N3O
- 분자량:315.37
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
All Caspase Isoforms
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Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HCT-15 | IC50 |
0.46 μM
Compound: 14
|
Cytotoxicity against human HCT15 cells measured after 2 days by MTT assay
Cytotoxicity against human HCT15 cells measured after 2 days by MTT assay
|
[PMID: 26334499] |
| HeLa | IC50 |
0.05 μM
Compound: 14
|
Cytotoxicity against human HeLa cells measured after 2 days by MTT assay
Cytotoxicity against human HeLa cells measured after 2 days by MTT assay
|
[PMID: 26334499] |
| T47D | IC50 |
>50 μM
Compound: 14
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Cytotoxicity against human T47D cells measured after 2 days by MTT assay
Cytotoxicity against human T47D cells measured after 2 days by MTT assay
|
[PMID: 26334499] |
Chemical Information
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CAS No. 1431362-93-4
-
분자량 315.37
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화학식 C20H17N3O
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SMILES
O=C1N=C(C2=C3C=CC=CC3=CC=C2)NC4=CC=C(N(C)C)C=C14
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선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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