Flavipucine
Flavipucine (Flavipucin), a glutarimide antibiotic, is found in the strain of Aspergillus flavipes F-2090/7. Flavipucine has antibacterial activity against B. subtilis. Flavipucine has antiprotozoal activity. Flavipucine has cytotoxic activity against several cancer cells.
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- CAS No.: 38473-18-6
- 화학식: C12H15NO4
- 분자량:237.25
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
1.6 μM
Compound: (-)-1
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Cytotoxicity against human HL60 cells assessed as reduction in cell viability incubated for 48 hrs by WST8 dye based assay
Cytotoxicity against human HL60 cells assessed as reduction in cell viability incubated for 48 hrs by WST8 dye based assay
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[PMID: 30935798] |
Chemical Information
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CAS No. 38473-18-6
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분자량 237.25
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화학식 C12H15NO4
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SMILES
CC(C)CC([C@H]1[C@]2(C(C=C(NC2=O)C)=O)O1)=O
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Synonyms
Flavipucin
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Kusakabe Y, et al. Synthesis, antibacterial and cytotoxic evaluation of flavipucine and its derivatives. Bioorg Med Chem Lett. 2019 Jun 1;29(11):1390-1394. [Content Brief]
[2]. Boya P CA, et al. Antiprotozoal Natural Products from Endophytic Fungi Associated with Cacao and Coffee. Metabolites. 2024 Oct 25;14(11):575. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Flavipucine Related Classifications
HY-N14364 Related Classifications
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