FUB 349
FUB 349 (Compound 8) is a selective Aromatase inhibitor with an IC50 of 12 μM. FUB 349 is also a H3 receptor antagonist with Kis of 12 and 2.1 nM for rH3R and hH3R, respectively. FUB 349 can be used for neurological diseases such as cognitive impairment research.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 184023-52-7
- 화학식: C13H16N2
- 분자량:200.28
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
All Histamine Receptor Isoforms
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Biological Activity
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Aromatase 50 μM (IC50) |
human H3 receptor 2.1 nM (Ki) |
rat H3 receptor 12 nM (Ki) |
Chemical Information
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CAS No. 184023-52-7
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분자량 200.28
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화학식 C13H16N2
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SMILES
C1(CCCCC2=CC=CC=C2)=CN=CN1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Karjalainen A, et al. Synthesis of new potent and selective aromatase inhibitors based on long-chained diarylalkylimidazole and diarylalkyltriazole molecule skeletons. Eur J Pharm Sci. 2000 Aug;11(2):109-31. [Content Brief]
[2]. Ligneau X, et al. Distinct pharmacology of rat and human histamine H(3) receptors: role of two amino acids in the third transmembrane domain. Br J Pharmacol. 2000 Dec;131(7):1247-50. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
FUB 349 Related Classifications
HY-123278 Related Classifications
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