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Cat. No.: HY-145356

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HbF inducer-1

HbF inducer-1 is an orally bioavailable fetal hemoglobin inducer.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 2987004-95-3
화학식: C₁₈H₁₉N₃O₃
분자량:325.36

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

HbF inducer-1 Chemical Structure

CAS No.: 2987004-95-3

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

HbF inducer-1 is an orally bioavailable fetal hemoglobin inducer.

All Histone Methyltransferase Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
CD34-positive (myeloid/lymphoid) cell	EC₅₀	2.8 μM Compound: 18	Induction of fetal hemoglobin in human bone marrow derived CD34+ cells incubated for 5 days by FITC staining based flow cytometry analysis Induction of fetal hemoglobin in human bone marrow derived CD34+ cells incubated for 5 days by FITC staining based flow cytometry analysis	[PMID: 32717372]

Chemical Information

CAS No. 2987004-95-3
분자량 325.36
화학식 C₁₈H₁₉N₃O₃
SMILES

CC(N1CC2(C1)CC(C2)NC(C3=CC(C4=CC=CC=C4)=NO3)=O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Katayama K, et al. Design, synthesis, and optimization of a series of 2-azaspiro[3.3]heptane derivatives as orally bioavailable fetal hemoglobin inducers. Bioorg Med Chem Lett. 2020 Oct 1;30(19):127425. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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HbF inducer-1

All Histone Methyltransferase Isoforms