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Cat. No.: HY-117922

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JYL-79

JYL-79 is a TRPV1 agonist with the IC₅₀ of 3.9 nM. JYL-79 can be used for study of neuropathic pain.

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CAS No.: 289902-64-3
화학식: C₂₆H₃₆N₂O₄S
분자량:472.64

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

JYL-79 Chemical Structure

CAS No.: 289902-64-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

JYL-79 is a TRPV1 agonist with the IC₅₀ of 3.9 nM. JYL-79 can be used for study of neuropathic pain^[1].

All TRP Channel Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	EC₅₀	1.97 nM Compound: 1	In vitro [Ca2+] influx relative to capsaicin by Rat Vanilloid receptor (VR1) expressing CHO cells In vitro [Ca2+] influx relative to capsaicin by Rat Vanilloid receptor (VR1) expressing CHO cells	[PMID: 12825950]
CHO	EC₅₀	1.97 nM Compound: 2	Agonist activity at rat TRPV1 expressed in CHO cells assessed as maximal calcium uptake Agonist activity at rat TRPV1 expressed in CHO cells assessed as maximal calcium uptake	[PMID: 17035013]

Chemical Information

CAS No. 289902-64-3
분자량 472.64
화학식 C₂₆H₃₆N₂O₄S
SMILES

CC(C)(C)C(OCC(CNC(NCC1=CC=C(O)C(OC)=C1)=S)CC2=CC=C(C)C(C)=C2)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Czikora Á, et al. Structure-activity relationships of vanilloid receptor agonists for arteriolar TRPV1. Br J Pharmacol. 2012 Mar;165(6):1801-1812. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

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수량:

JYL-79

All TRP Channel Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

JYL-79 Related Classifications

HY-117922 Related Classifications