LHQ766
LHQ766 is a highly selective, orally active, covalent FGFR2 inhibitor with an IC50 of 7.3 nM. LHQ766 significantly suppresses phosphorylation of FGFR2 and its downstream signaling molecules FRS2-a, Akt and ERK1/2. LHQ766 selectively suppresses the proliferation of FGFR2-driven cancer cells.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C28H27F2N5O3
- 분자량:519.54
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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FGFR2 7.3 nM (IC50) |
ERK1 |
ERK2 |
Chemical Information
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분자량 519.54
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화학식 C28H27F2N5O3
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SMILES
CC(C=C1NC(C(F)=C)=O)=C(C=C1)C2=C(C3=C(N=CN=C3N2C)N)C4=CC(F)=C(C=C4)C5(COC5)OCC
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LHQ766 Related Classifications
HY-180794 Related Classifications
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