Norcyclizine
Based on 1 Customer Validation
Norcyclizine is a piperazine compound that can be used for the synthesis of antimicrobial agents. 1-Benzhydrylpiperazine derivatives have been found to enhance the antibacterial activity of β-lactam antibiotics (Oxacillin, HY-B0925A) against Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA). This enhancement is likely achieved by inhibiting the allosteric site of PBP2a. Additionally, 1-Benzhydrylpiperazine can also serve as a pharmacological scaffold for the synthesis of anticancer agents.
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- CAS No.: 841-77-0
- 화학식: C17H20N2
- 분자량:252.35
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보관:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Biological Activity
Chemical Information
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CAS No. 841-77-0
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Appearance Solid
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분자량 252.35
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화학식 C17H20N2
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Color White to off-white
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SMILES
C1(C(N2CCNCC2)C3=CC=CC=C3)=CC=CC=C1
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Synonyms
1-(Diphenylmethyl)piperazine; 1-Benzhydrylpiperazine
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
순도&문서
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Data Sheet (270 KB)
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SDS (950 KB)
- English - EN (950 KB)
- Français - FR (950 KB)
- Deutsch - DE (950 KB)
- Norwegian - NO (950 KB)
- Español - ES (950 KB)
- Swedish - SV (950 KB)
- Italian - IT (950 KB)
- Korean - KR (950 KB)
- Portuguese - PT (950 KB)
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Handling Instructions (2659 KB)
References
[1]. Witek K, et al. Chalcogen-Varied Imidazolone Derivatives as Antibiotic Resistance Breakers in Staphylococcus aureus Strains. Antibiotics (Basel). 2023 Nov 11;12(11):1618. [Content Brief]
[2]. Ananda Kumar CS et al. Synthesis and in vitro antiproliferative activity of novel 1-benzhydrylpiperazine derivatives against human cancer cell lines. Eur J Med Chem. 2009 Mar;44(3):1223-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Norcyclizine Related Classifications
HY-W013376 Related Classifications
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