PF-06465603
PF-06465603 is a highly potent and selective ATP-competitive kinase inhibitor and a class 1 PI3K and mTOR inhibitor. PF-06465603 is a metabolite of PF-04691502 with a terminal carboxylic acid structure.
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- CAS No.: 1431626-44-6
- 화학식: C22H25N5O5
- 분자량:439.46
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BT-20 | IC50 |
2070 nM
Compound: 10, PF-06465603
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Inhibition of AKT phosphorylation at Ser 473 in human BT20 cells
Inhibition of AKT phosphorylation at Ser 473 in human BT20 cells
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[PMID: 23506825] |
Chemical Information
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CAS No. 1431626-44-6
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분자량 439.46
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화학식 C22H25N5O5
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SMILES
O=C(O)CO[C@@H]1CC[C@@H](N(C2=NC(N)=NC(C)=C2C=C3C4=CC=C(OC)N=C4)C3=O)CC1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PF-06465603 Related Classifications
HY-117923 Related Classifications
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